Cargando…

Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App(NL-G-F), App(NL-F), and wild type mice

Epigenetic mechanisms occurring in the brain as well as alterations in the gut microbiome composition might contribute to Alzheimer’s disease (AD). Human amyloid precursor protein knock-in (KI) mice contain the Swedish and Iberian mutations (App(NL-F)) or those two and also the Arctic mutation (App(...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kundu, Payel, Torres, Eileen Ruth S., Stagaman, Keaton, Kasschau, Kristin, Okhovat, Mariam, Holden, Sarah, Ward, Samantha, Nevonen, Kimberly A., Davis, Brett A., Saito, Takashi, Saido, Takaomi C., Carbone, Lucia, Sharpton, Thomas J., Raber, Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907263/ https://www.ncbi.nlm.nih.gov/pubmed/33633159 http://dx.doi.org/10.1038/s41598-021-83851-4

Ejemplares similares

Fecal Implants From App(NL–G–F) and App(NL–G–F/E4) Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice
por: Kundu, Payel, et al.
Publicado: (2022)

Assessments of prolonged effects of desflurane and sevoflurane on motor learning deficits in aged App(NL-G-F/NL-G-F) mice
por: Niikura, Ryo, et al.
Publicado: (2022)

Age-Dependent Behavioral and Metabolic Assessment of App(NL−G−F/NL−G−F) Knock-in (KI) Mice
por: Wang, Shanshan, et al.
Publicado: (2022)

Regional contributions of D-serine to Alzheimer’s disease pathology in male App(NL–G–F/NL–G–F) mice
por: Ni, Xiance, et al.
Publicado: (2023)

Retinal Thickness Changes Over Time in a Murine AD Model APP(NL-F/NL-F)
por: Salobrar-García, Elena, et al.
Publicado: (2021)

A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App (NL−F/NL−F) knock‐in mouse model
por: Mazzei, Guianfranco, et al.
Publicado: (2021)

Spatial reversal learning defect coincides with hypersynchronous telencephalic BOLD functional connectivity in APP(NL-F/NL-F) knock-in mice
por: Shah, Disha, et al.
Publicado: (2018)

The two faces of synaptic failure in App(NL-G-F) knock-in mice
por: Latif-Hernandez, Amira, et al.
Publicado: (2020)

Astaxanthin Ameliorated Parvalbumin-Positive Neuron Deficits and Alzheimer’s Disease-Related Pathological Progression in the Hippocampus of App(NL-G-F/NL-G-F) Mice
por: Hongo, Nobuko, et al.
Publicado: (2020)

Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in App(NL-G-F), App(NL-F), and 3xTg-AD mouse models
por: Pauls, Eduardo, et al.
Publicado: (2021)

Amyloid β induces interneuron-specific changes in the hippocampus of APP(NL-F) mice
por: Sos, Katalin E., et al.
Publicado: (2020)

Increased Insoluble Amyloid-β Induces Negligible Cognitive Deficits in Old App(NL/NL) Knock-In Mice
por: Salas, Isabel H., et al.
Publicado: (2018)

β-secretase inhibition prevents structural spine plasticity deficits in App(NL-G-F) mice
por: Blume, Tanja, et al.
Publicado: (2022)

Cerebral Aβ deposition precedes reduced cerebrospinal fluid and serum Aβ42/Aβ40 ratios in the App(NL−F/NL−F) knock-in mouse model of Alzheimer’s disease
por: Andersson, Emelie, et al.
Publicado: (2023)

Effects of high‐fat diet on nutrient metabolism and cognitive functions in young APPKI(NL‐G‐F/NL‐G‐F) mice
por: Wang, Wei, et al.
Publicado: (2022)

Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice
por: Park, Hanseul, et al.
Publicado: (2023)

The App(NL-G-F) mouse retina is a site for preclinical Alzheimer’s disease diagnosis and research
por: Vandenabeele, Marjan, et al.
Publicado: (2021)

Pathological and neurophysiological outcomes of seeding human-derived tau pathology in the APP-KI NL-G-F and NL-NL mouse models of Alzheimer’s Disease
por: Tok, S., et al.
Publicado: (2022)

Somatostatin slows Aβ plaque deposition in aged APP(NL-F/NL-F) mice by blocking Aβ aggregation
por: Williams, Declan, et al.
Publicado: (2023)

Detection of Amyloid β Oligomers with RNA Aptamers in App(NL-G-F/NL-G-F) Mice: A Model of Arctic Alzheimer’s Disease
por: Obata, Yayoi, et al.
Publicado: (2020)

Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in App(NL-G-F/NL-G-F) mice
por: Emre, Ceren, et al.
Publicado: (2022)

Early memory deficits and extensive brain network disorganization in the App(NL-F)/MAPT double knock-in mouse model of familial Alzheimer’s disease
por: Borcuk, Christopher, et al.
Publicado: (2022)

Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer’s Disease in App(NL-G-F) Mice
por: Sahu, Bijayani, et al.
Publicado: (2023)

Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APP(NL-F) mouse model of Alzheimer disease
por: Wang, Hansen, et al.
Publicado: (2017)

The Roles of Long-Term Hyperhomocysteinemia and Micronutrient Supplementation in the App(NL–G–F) Model of Alzheimer’s Disease
por: Nieraad, Hendrik, et al.
Publicado: (2022)

Mitochondrial Alterations in Neurons Derived from the Murine App(NL-F) Knock-In Model of Alzheimer’s Disease
por: Dentoni, Giacomo, et al.
Publicado: (2022)

Increase in Tau Pathology in P290S Mapt Knock-In Mice Crossed with App(NL-G-F) Mice
por: Huang, Melissa, et al.
Publicado: (2022)

SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in App(NL-G-F/NL-G-F) Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling
por: Izumi, Hisanao, et al.
Publicado: (2020)

General formula for the running of local fNL
por: Byrnes, Christian T., et al.
Publicado: (2012)

Low-grade peripheral inflammation affects brain pathology in the App(NL-G-F)mouse model of Alzheimer’s disease
por: Xie, Junhua, et al.
Publicado: (2021)

Accumulation of m(6)A exhibits stronger correlation with MAPT than β-amyloid pathology in an APP(NL-G-F) /MAPT(P301S) mouse model of Alzheimer’s disease
por: Jiang, Lulu, et al.
Publicado: (2023)

Accumulation of m(6)A exhibits stronger correlation with MAPT than β-amyloid pathology in an APP(NL-G-F) /MAPT(P301S) mouse model of Alzheimer’s disease
por: Jiang, Lulu, et al.
Publicado: (2023)

Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App(NL−G−F) knock-in Alzheimer mice
por: Tambaro, Simone, et al.
Publicado: (2023)

Hippocampus of the APP(NL–G–F) mouse model of Alzheimer’s disease exhibits region-specific tissue softening concomitant with elevated astrogliosis
por: Hall, Chloe M., et al.
Publicado: (2023)

Early-stage mapping of macromolecular content in APP(NL-F) mouse model of Alzheimer’s disease using nuclear Overhauser effect MRI
por: Swain, Anshuman, et al.
Publicado: (2023)

Role of nuclear receptors NlHR3 and NlFTZ-F1 in regulating molting and reproduction in Nilaparvata lugens (stål)
por: Li, Kailong, et al.
Publicado: (2023)

Corrigendum: Hippocampus of the APP(NL−G−F) mouse model of Alzheimer's disease exhibits region-specific tissue softening concomitant with elevated astrogliosis
por: Hall, Chloe M., et al.
Publicado: (2023)

The Expression of the Endocannabinoid Receptors CB2 and GPR55 Is Highly Increased during the Progression of Alzheimer’s Disease in App(NL-G-F) Knock-In Mice
por: Medina-Vera, Dina, et al.
Publicado: (2023)

Combined Effects of Three High-Energy Charged Particle Beams Important for Space Flight on Brain, Behavioral and Cognitive Endpoints in B6D2F1 Female and Male Mice
por: Raber, Jacob, et al.
Publicado: (2019)

Behavioral and Cognitive Performance Following Exposure to Second-Hand Smoke (SHS) from Tobacco Products Associated with Oxidative-Stress-Induced DNA Damage and Repair and Disruption of the Gut Microbiome
por: Raber, Jacob, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j02odlfc8tllgg2cq7m59jqs0d