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Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha

Thyroid hormone signaling plays an essential role in muscle development and function, in the maintenance of muscle mass, and in regeneration after injury, via activation of thyroid nuclear receptor alpha (THRA). A mouse model of resistance to thyroid hormone carrying a frame-shift mutation in the TH...

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Detalles Bibliográficos
Autores principales: Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-yann, Brent, Gregory A., Perin, Laura, Milanesi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907286/
https://www.ncbi.nlm.nih.gov/pubmed/33633251
http://dx.doi.org/10.1038/s41598-021-84080-5

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