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Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha
Thyroid hormone signaling plays an essential role in muscle development and function, in the maintenance of muscle mass, and in regeneration after injury, via activation of thyroid nuclear receptor alpha (THRA). A mouse model of resistance to thyroid hormone carrying a frame-shift mutation in the TH...
Autores principales: | Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-yann, Brent, Gregory A., Perin, Laura, Milanesi, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907286/ https://www.ncbi.nlm.nih.gov/pubmed/33633251 http://dx.doi.org/10.1038/s41598-021-84080-5 |
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