Cargando…

A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea

To evaluate whether the percentage of total sleep time spent with apnoea and hypopnoea duration time (AHT%) is better than the apnoea-hypopnoea index (AHI) for the assessment of nocturnal hypoxaemia and excessive daytime sleepiness (EDS) in patients with obstructive sleep apnoea (OSA). Patients with...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Changxiu, Zhang, Ying, Liu, Jiuyu, Sun, Gengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907378/
https://www.ncbi.nlm.nih.gov/pubmed/33633338
http://dx.doi.org/10.1038/s41598-021-84239-0
_version_ 1783655486474682368
author Ma, Changxiu
Zhang, Ying
Liu, Jiuyu
Sun, Gengyun
author_facet Ma, Changxiu
Zhang, Ying
Liu, Jiuyu
Sun, Gengyun
author_sort Ma, Changxiu
collection PubMed
description To evaluate whether the percentage of total sleep time spent with apnoea and hypopnoea duration time (AHT%) is better than the apnoea-hypopnoea index (AHI) for the assessment of nocturnal hypoxaemia and excessive daytime sleepiness (EDS) in patients with obstructive sleep apnoea (OSA). Patients with suspected OSA were enrolled. Polysomnography, Epworth Sleepiness Scale, self-administered surveys and anthropometric measures were performed. The efficiency of AHT% and the AHI was evaluated for nocturnal hypoxaemia and EDS. A total of 160 eligible participants were analysed. The median AHT% in normal, mild, moderate and severe OSA patients was significantly different in the four-group patients with OSA. Spearman rank correlations analysis found that the associations were stronger between AHT% with percentage of total sleep time and O(2) saturation of < 90% and minimum nocturnal oxygen saturation than these parameters with the AHI. AHT% had a greater area under the curve than the AHI for predicting EDS in patients with OSA. AHT% was significantly higher in the EDS group. We present a novel parameter, AHT%, to evaluate nocturnal hypoxaemia and EDS in OSA patients. AHT% partially compensates for the shortcomings of the AHI. AHT% is better than the AHI for assessing nocturnal hypoxaemia and EDS. AHT% reflects different clinical characteristics associated with OSA from a new perspective.
format Online
Article
Text
id pubmed-7907378
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-79073782021-03-02 A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea Ma, Changxiu Zhang, Ying Liu, Jiuyu Sun, Gengyun Sci Rep Article To evaluate whether the percentage of total sleep time spent with apnoea and hypopnoea duration time (AHT%) is better than the apnoea-hypopnoea index (AHI) for the assessment of nocturnal hypoxaemia and excessive daytime sleepiness (EDS) in patients with obstructive sleep apnoea (OSA). Patients with suspected OSA were enrolled. Polysomnography, Epworth Sleepiness Scale, self-administered surveys and anthropometric measures were performed. The efficiency of AHT% and the AHI was evaluated for nocturnal hypoxaemia and EDS. A total of 160 eligible participants were analysed. The median AHT% in normal, mild, moderate and severe OSA patients was significantly different in the four-group patients with OSA. Spearman rank correlations analysis found that the associations were stronger between AHT% with percentage of total sleep time and O(2) saturation of < 90% and minimum nocturnal oxygen saturation than these parameters with the AHI. AHT% had a greater area under the curve than the AHI for predicting EDS in patients with OSA. AHT% was significantly higher in the EDS group. We present a novel parameter, AHT%, to evaluate nocturnal hypoxaemia and EDS in OSA patients. AHT% partially compensates for the shortcomings of the AHI. AHT% is better than the AHI for assessing nocturnal hypoxaemia and EDS. AHT% reflects different clinical characteristics associated with OSA from a new perspective. Nature Publishing Group UK 2021-02-25 /pmc/articles/PMC7907378/ /pubmed/33633338 http://dx.doi.org/10.1038/s41598-021-84239-0 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Ma, Changxiu
Zhang, Ying
Liu, Jiuyu
Sun, Gengyun
A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
title A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
title_full A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
title_fullStr A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
title_full_unstemmed A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
title_short A novel parameter is better than the AHI to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
title_sort novel parameter is better than the ahi to assess nocturnal hypoxaemia and excessive daytime sleepiness in obstructive sleep apnoea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907378/
https://www.ncbi.nlm.nih.gov/pubmed/33633338
http://dx.doi.org/10.1038/s41598-021-84239-0
work_keys_str_mv AT machangxiu anovelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT zhangying anovelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT liujiuyu anovelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT sungengyun anovelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT machangxiu novelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT zhangying novelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT liujiuyu novelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea
AT sungengyun novelparameterisbetterthantheahitoassessnocturnalhypoxaemiaandexcessivedaytimesleepinessinobstructivesleepapnoea