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c-Jun Amino Terminal Kinase Signaling Promotes Aristolochic Acid-Induced Acute Kidney Injury

Aristolochic acid (AA) is a toxin that induces DNA damage in tubular epithelial cells of the kidney and is the cause of Balkan Nephropathy and Chinese Herb Nephropathy. In cultured tubular epithelial cells, AA induces a pro-fibrotic response via the c-Jun amino terminal kinase (JNK) signaling pathwa...

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Detalles Bibliográficos
Autores principales:	Yang, Fan, Ozols, Elyce, Ma, Frank Y., Leong, Khai Gene, Tesch, Greg H., Jiang, Xiaoyun, Nikolic-Paterson, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907440/ https://www.ncbi.nlm.nih.gov/pubmed/33643061 http://dx.doi.org/10.3389/fphys.2021.599114

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