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An Attenuated Escherichia coli K88ac LT(S63K)ΔSTb Efficiently Provides Protection Against Enterotoxigenic Escherichia coli in the Mouse Model

To develop an attenuated vaccine candidate against K88ac enterotoxigenic Escherichia coli (ETEC), a novel Escherichia coli (E. coli) K88ac LT(S63K)ΔSTb with LT(S63K) mutation and ST1 deletion was generated using site mutagenesis and λ-Red homologous recombination based on wild paternal ETEC strain C...

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Detalles Bibliográficos
Autores principales:	Zhang, Xinyu, Yu, Shupei, Cheng, Darong, Feng, Yu, Yang, Yuefei, Sun, Huaichang, Ding, Jiabo, Wang, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907446/ https://www.ncbi.nlm.nih.gov/pubmed/33644141 http://dx.doi.org/10.3389/fvets.2020.620255

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