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Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong

Sea lice (Copepoda: Caligidae) are ectoparasites which negatively impact marine aquaculture species around the world. There are a limited number of treatments licensed for use against sea lice in tropical and semi-tropical farmed fish species. Emamectin benzoate (EB) was an effective pharmaceutical...

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Autores principales: St-Hilaire, Sophie, Cheng, Tzu Hsuan, Chan, Stephen Chi Ho, Leung, Chi Fai, Chan, Ka Man, Lim, Kwok Zu, Furtado, William, Bastos Gomes, Giana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907643/
https://www.ncbi.nlm.nih.gov/pubmed/33644159
http://dx.doi.org/10.3389/fvets.2021.646652
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author St-Hilaire, Sophie
Cheng, Tzu Hsuan
Chan, Stephen Chi Ho
Leung, Chi Fai
Chan, Ka Man
Lim, Kwok Zu
Furtado, William
Bastos Gomes, Giana
author_facet St-Hilaire, Sophie
Cheng, Tzu Hsuan
Chan, Stephen Chi Ho
Leung, Chi Fai
Chan, Ka Man
Lim, Kwok Zu
Furtado, William
Bastos Gomes, Giana
author_sort St-Hilaire, Sophie
collection PubMed
description Sea lice (Copepoda: Caligidae) are ectoparasites which negatively impact marine aquaculture species around the world. There are a limited number of treatments licensed for use against sea lice in tropical and semi-tropical farmed fish species. Emamectin benzoate (EB) was an effective pharmaceutical drug against sea lice infestations in several salmon industries before resistance to the product developed. This drug has not been extensively tested in marine fish within Asia. The objective of this study was to determine whether this drug could be used to treat oral infections with sea lice in hybrid grouper (Mycteroperca tigris × Epinephelus lanceolatus) cultured in saltwater net-pen sites in Hong Kong. We observed an overall reduction in sea lice infections over time, starting on the last day of the treatment up to the end of our study (i.e., 14 days after the last EB treatment). We also observed a large variation in concentrations of EB in fish on the last day of the treatment, which provides an explanation for the variation in response to the treatment. It also suggests that distribution of the medication to fish in saltwater net-pens is difficult, especially when medication is hand-mixed in the feed and possibly unevenly distributed in the daily rations. Overall, this study provides preliminary evidence that EB could be used to treat sea lice found in Hong Kong and potentially in other regions of SE Asia.
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spelling pubmed-79076432021-02-27 Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong St-Hilaire, Sophie Cheng, Tzu Hsuan Chan, Stephen Chi Ho Leung, Chi Fai Chan, Ka Man Lim, Kwok Zu Furtado, William Bastos Gomes, Giana Front Vet Sci Veterinary Science Sea lice (Copepoda: Caligidae) are ectoparasites which negatively impact marine aquaculture species around the world. There are a limited number of treatments licensed for use against sea lice in tropical and semi-tropical farmed fish species. Emamectin benzoate (EB) was an effective pharmaceutical drug against sea lice infestations in several salmon industries before resistance to the product developed. This drug has not been extensively tested in marine fish within Asia. The objective of this study was to determine whether this drug could be used to treat oral infections with sea lice in hybrid grouper (Mycteroperca tigris × Epinephelus lanceolatus) cultured in saltwater net-pen sites in Hong Kong. We observed an overall reduction in sea lice infections over time, starting on the last day of the treatment up to the end of our study (i.e., 14 days after the last EB treatment). We also observed a large variation in concentrations of EB in fish on the last day of the treatment, which provides an explanation for the variation in response to the treatment. It also suggests that distribution of the medication to fish in saltwater net-pens is difficult, especially when medication is hand-mixed in the feed and possibly unevenly distributed in the daily rations. Overall, this study provides preliminary evidence that EB could be used to treat sea lice found in Hong Kong and potentially in other regions of SE Asia. Frontiers Media S.A. 2021-02-12 /pmc/articles/PMC7907643/ /pubmed/33644159 http://dx.doi.org/10.3389/fvets.2021.646652 Text en Copyright © 2021 St-Hilaire, Cheng, Chan, Leung, Chan, Lim, Furtado and Bastos Gomes. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
St-Hilaire, Sophie
Cheng, Tzu Hsuan
Chan, Stephen Chi Ho
Leung, Chi Fai
Chan, Ka Man
Lim, Kwok Zu
Furtado, William
Bastos Gomes, Giana
Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong
title Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong
title_full Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong
title_fullStr Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong
title_full_unstemmed Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong
title_short Emamectin Benzoate Treatment of Hybrid Grouper Infected With Sea Lice in Hong Kong
title_sort emamectin benzoate treatment of hybrid grouper infected with sea lice in hong kong
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907643/
https://www.ncbi.nlm.nih.gov/pubmed/33644159
http://dx.doi.org/10.3389/fvets.2021.646652
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