Human Mesenchymal Stem Cell-Derived Exosomal microRNA-143 Promotes Apoptosis and Suppresses Cell Growth in Pancreatic Cancer via Target Gene Regulation

BACKGROUND: This study aimed to explore the regulatory mechanism of hsa-miR-143-3p and lncRNA RP11-363N22.3–functioning upstream of KRAS–in exosomes derived from human mesenchymal stem cells (hMSCs) in pancreatic cancer. METHODS: Western blotting and quantitative PCR were used to determine gene expr...

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Detalles Bibliográficos
Autores principales: Wang, Bingyi, Xu, Yan, Wei, Yuhua, Lv, Lixin, Liu, Nanbin, Lin, Rui, Wang, Xiuyan, Shi, Baomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907650/
https://www.ncbi.nlm.nih.gov/pubmed/33643376
http://dx.doi.org/10.3389/fgene.2021.581694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907650/
https://www.ncbi.nlm.nih.gov/pubmed/33643376
http://dx.doi.org/10.3389/fgene.2021.581694

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