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Human Mesenchymal Stem Cell-Derived Exosomal microRNA-143 Promotes Apoptosis and Suppresses Cell Growth in Pancreatic Cancer via Target Gene Regulation
BACKGROUND: This study aimed to explore the regulatory mechanism of hsa-miR-143-3p and lncRNA RP11-363N22.3–functioning upstream of KRAS–in exosomes derived from human mesenchymal stem cells (hMSCs) in pancreatic cancer. METHODS: Western blotting and quantitative PCR were used to determine gene expr...
Autores principales: | Wang, Bingyi, Xu, Yan, Wei, Yuhua, Lv, Lixin, Liu, Nanbin, Lin, Rui, Wang, Xiuyan, Shi, Baomin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907650/ https://www.ncbi.nlm.nih.gov/pubmed/33643376 http://dx.doi.org/10.3389/fgene.2021.581694 |
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