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Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network

With increasing interest in stereotactic body radiotherapy (SBRT) for unresectable pancreatic cancer, quality improvement (QI) initiatives to develop integrated clinical workflows are crucial to ensure quality assurance (QA) when introducing this challenging technique into radiation practices. Mater...

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Autores principales: Augustyn, Alexander, Reed, Valerie I., Ahmad, Neelofur, Bhutani, Manoop S., Bloom, Elizabeth S., Bowers, John R., Chronowski, Gregory M., Das, Prajnan, Holliday, Emma B., Delclos, Marc E., Huey, Ryan W., Koay, Eugene J., Lee, Sunyoung S., Nelson, Christopher L., Taniguchi, Cullen M., Koong, Albert C., Chun, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907676/
https://www.ncbi.nlm.nih.gov/pubmed/33665384
http://dx.doi.org/10.1016/j.ctro.2021.02.004
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author Augustyn, Alexander
Reed, Valerie I.
Ahmad, Neelofur
Bhutani, Manoop S.
Bloom, Elizabeth S.
Bowers, John R.
Chronowski, Gregory M.
Das, Prajnan
Holliday, Emma B.
Delclos, Marc E.
Huey, Ryan W.
Koay, Eugene J.
Lee, Sunyoung S.
Nelson, Christopher L.
Taniguchi, Cullen M.
Koong, Albert C.
Chun, Stephen G.
author_facet Augustyn, Alexander
Reed, Valerie I.
Ahmad, Neelofur
Bhutani, Manoop S.
Bloom, Elizabeth S.
Bowers, John R.
Chronowski, Gregory M.
Das, Prajnan
Holliday, Emma B.
Delclos, Marc E.
Huey, Ryan W.
Koay, Eugene J.
Lee, Sunyoung S.
Nelson, Christopher L.
Taniguchi, Cullen M.
Koong, Albert C.
Chun, Stephen G.
author_sort Augustyn, Alexander
collection PubMed
description With increasing interest in stereotactic body radiotherapy (SBRT) for unresectable pancreatic cancer, quality improvement (QI) initiatives to develop integrated clinical workflows are crucial to ensure quality assurance (QA) when introducing this challenging technique into radiation practices. Materials/Methods: In 2017, we used the Plan, Do, Study, Act (PDSA) QI methodology to implement a new pancreas SBRT program in an integrated community radiation oncology satellite. A unified integrated information technology infrastructure was used to virtually integrate the planned workflow into the community radiation oncology satellite network (P – Plan/D – Do). This workflow included multiple prospective quality assurance (QA) measures including multidisciplinary evaluation, prospective scrutiny of radiation target delineation, prospective radiation plan evaluation, and monitoring of patient outcomes. Institutional review board approval was obtained to retrospectively study and report outcomes of patients treated in this program (S – Study). Results: There were 12 consecutive patients identified who were treated in this program from 2017 to 2020 with a median follow-up of 27 months. The median survival was 13 months, median local failure free survival was 12 months and median progression free survival was 6 months from SBRT. There were no acute or late Common Terminology Criteria for Adverse Effects (CTCAE) version 5 toxicities ≥ Grade 3. Conclusion: We report the successful implementation of a community pancreas SBRT program involving multiple prospective QA measures, providing the groundwork to safely expand access to pancreas SBRT in our community satellite network (A – Act).
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spelling pubmed-79076762021-03-03 Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network Augustyn, Alexander Reed, Valerie I. Ahmad, Neelofur Bhutani, Manoop S. Bloom, Elizabeth S. Bowers, John R. Chronowski, Gregory M. Das, Prajnan Holliday, Emma B. Delclos, Marc E. Huey, Ryan W. Koay, Eugene J. Lee, Sunyoung S. Nelson, Christopher L. Taniguchi, Cullen M. Koong, Albert C. Chun, Stephen G. Clin Transl Radiat Oncol Technical Note With increasing interest in stereotactic body radiotherapy (SBRT) for unresectable pancreatic cancer, quality improvement (QI) initiatives to develop integrated clinical workflows are crucial to ensure quality assurance (QA) when introducing this challenging technique into radiation practices. Materials/Methods: In 2017, we used the Plan, Do, Study, Act (PDSA) QI methodology to implement a new pancreas SBRT program in an integrated community radiation oncology satellite. A unified integrated information technology infrastructure was used to virtually integrate the planned workflow into the community radiation oncology satellite network (P – Plan/D – Do). This workflow included multiple prospective quality assurance (QA) measures including multidisciplinary evaluation, prospective scrutiny of radiation target delineation, prospective radiation plan evaluation, and monitoring of patient outcomes. Institutional review board approval was obtained to retrospectively study and report outcomes of patients treated in this program (S – Study). Results: There were 12 consecutive patients identified who were treated in this program from 2017 to 2020 with a median follow-up of 27 months. The median survival was 13 months, median local failure free survival was 12 months and median progression free survival was 6 months from SBRT. There were no acute or late Common Terminology Criteria for Adverse Effects (CTCAE) version 5 toxicities ≥ Grade 3. Conclusion: We report the successful implementation of a community pancreas SBRT program involving multiple prospective QA measures, providing the groundwork to safely expand access to pancreas SBRT in our community satellite network (A – Act). Elsevier 2021-02-12 /pmc/articles/PMC7907676/ /pubmed/33665384 http://dx.doi.org/10.1016/j.ctro.2021.02.004 Text en © 2021 The Authors. Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Augustyn, Alexander
Reed, Valerie I.
Ahmad, Neelofur
Bhutani, Manoop S.
Bloom, Elizabeth S.
Bowers, John R.
Chronowski, Gregory M.
Das, Prajnan
Holliday, Emma B.
Delclos, Marc E.
Huey, Ryan W.
Koay, Eugene J.
Lee, Sunyoung S.
Nelson, Christopher L.
Taniguchi, Cullen M.
Koong, Albert C.
Chun, Stephen G.
Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
title Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
title_full Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
title_fullStr Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
title_full_unstemmed Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
title_short Implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
title_sort implementation of a stereotactic body radiotherapy program for unresectable pancreatic cancer in an integrated community academic radiation oncology satellite network
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907676/
https://www.ncbi.nlm.nih.gov/pubmed/33665384
http://dx.doi.org/10.1016/j.ctro.2021.02.004
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