Cargando…

miR-1254 induced by NESG1 inactivates HDGF/DDX5-stimulated nuclear translocation of β-catenin and suppresses NPC metastasis

Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in Chinese and other Southeast Asians. We aimed to explore the precise mechanism for NESG1 in NPC for understanding the pathogenesis of NPC. Transwell, Boyden assays, and wounding healing were respectively performed for cell m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Chao, Li, Wenmin, Peng, Xuemei, Liu, Xiong, Zhang, Ziyan, Liu, Zhen, Deng, Tongyuan, Luo, Rongcheng, Fang, Weiyi, Deng, Xiaojie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907678/ https://www.ncbi.nlm.nih.gov/pubmed/33718512 http://dx.doi.org/10.1016/j.omtm.2021.02.001

Ejemplares similares

Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma
por: Liu, Zhen, et al.
Publicado: (2011)

VPS33B interacts with NESG1 to modulate EGFR/PI3K/AKT/c-Myc/P53/miR-133a-3p signaling and induce 5-fluorouracil sensitivity in nasopharyngeal carcinoma
por: Liang, Zixi, et al.
Publicado: (2019)

VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer
por: Ning, Yingxia, et al.
Publicado: (2021)

CCDC65 as a new potential tumor suppressor induced by metformin inhibits activation of AKT1 via ubiquitination of ENO1 in gastric cancer
por: Deng, Tongyuan, et al.
Publicado: (2021)

The expression and clinical significance of HDGF in osteosarcoma
por: Chen, Zhiguo, et al.
Publicado: (2015)

Downregulation of HDGF inhibits the tumorigenesis of bladder cancer cells by inactivating the PI3K-AKT signaling pathway
por: Zhang, Cong, et al.
Publicado: (2019)

Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer
por: Zhou, Yanyan, et al.
Publicado: (2010)

Expression of Concern: Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma
Publicado: (2020)

Toxic effects of polychlorinated biphenyls (Aroclor 1254) on human sperm motility
por: Jiang, Li-Gang, et al.
Publicado: (2017)

NAP1L1 promotes the growth of colon cancer by activating HDGF/DDX5: NAP1L1 promotes colon cancer growth
por: Liang, Xuemin, et al.
Publicado: (2022)

High Nuclear Expression of HDGF Correlates with Disease Progression and Poor Prognosis in Human Endometrial Carcinoma
por: Wang, Lijing, et al.
Publicado: (2014)

Correction to Expression of Concern on: Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma
Publicado: (2020)

Effects of Aroclor 1254 on In Vivo Oocyte Maturation in the Mouse
por: Liu, ShuZhen, et al.
Publicado: (2014)

HBX-induced miR-5188 impairs FOXO1 to stimulate β-catenin nuclear translocation and promotes tumor stemness in hepatocellular carcinoma
por: Lin, Xian, et al.
Publicado: (2019)

MicroRNA-939 Directly Targets HDGF to Inhibit the Aggressiveness of Prostate Cancer via Deactivation of the WNT/β-Catenin Pathway
por: Situ, Jie, et al.
Publicado: (2020)

Hepatoma-Derived Growth Factor and DDX5 Promote Carcinogenesis and Progression of Endometrial Cancer by Activating β-Catenin
por: Liu, Chunhua, et al.
Publicado: (2019)

MicroRNA-939 Directly Targets HDGF to Inhibit the Aggressiveness of Prostate Cancer via Deactivation of the WNT/β-Catenin Pathway [Retraction]
Publicado: (2021)

microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway
por: Chen, Yiyu, et al.
Publicado: (2016)

CCNI2 promotes the progression of human gastric cancer through HDGF
por: Chen, Wenchao, et al.
Publicado: (2021)

Effects of Aroclor 1254 on Intestinal Immunity, Metabolism, and Microflora in Zebrafish
por: Zhu, Di-Hua, et al.
Publicado: (2022)

LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells
por: LeRoy, Gary, et al.
Publicado: (2019)

HDGF stimulates liver tumorigenesis by enhancing reactive oxygen species generation in mitochondria
por: Hu, Tsung-Hui, et al.
Publicado: (2023)

Cordycepin inhibits the proliferation and progression of NPC by targeting the MAPK/ERK and β-catenin pathways
por: Zhou, Yaqi, et al.
Publicado: (2022)

MicroRNA-95-3p inhibits cell proliferation and metastasis in colorectal carcinoma by HDGF
por: Hong, Yong-gang, et al.
Publicado: (2020)

Components of the LINC and NPC complexes coordinately target and translocate a virus into the nucleus to promote infection
por: Spriggs, Chelsey C., et al.
Publicado: (2022)

Embryonic Mortality and Chromosomal Alterations Caused by Aroclor 1254 in Ring Doves
por: Peakall, David B., et al.
Publicado: (1972)

The NPC, in detail
por: Robinson, Richard
Publicado: (2007)

MicroRNA-195 inhibits the behavior of cervical cancer tumors by directly targeting HDGF
por: Song, Rongrong, et al.
Publicado: (2017)

miR-4721, Induced by EBV-miR-BART22, Targets GSK3β to Enhance the Tumorigenic Capacity of NPC through the WNT/β-catenin Pathway
por: Tang, ZiBo, et al.
Publicado: (2020)

Identification and Classification of Rare Variants in NPC1 and NPC2 in Quebec
por: Touma, Lahoud, et al.
Publicado: (2021)

Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis
por: Lin, Yu-Wei, et al.
Publicado: (2019)

VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma
por: Yang, Shuo, et al.
Publicado: (2023)

Upregulation of miR-1254 promotes Hepatocellular Carcinoma Cell Proliferation, Migration, and Invasion via Inactivation of the Hippo-YAP signaling pathway by decreasing PAX5
por: Lu, Xu, et al.
Publicado: (2021)

Building and breaking the NPC
por: LeBrasseur, Nicole
Publicado: (2003)

DDX39 promotes hepatocellular carcinoma growth and metastasis through activating Wnt/β-catenin pathway
por: Zhang, Tong, et al.
Publicado: (2018)

Disruption of the Thyroid System by the Thyroid-Disrupting Compound Aroclor 1254 in Juvenile Japanese Flounder (Paralichthys olivaceus)
por: Dong, Yifei, et al.
Publicado: (2014)

Thermally induced formation of polychlorinated dibenzofurans from Aroclor 1254-contaminated mineral oil.
por: Narang, R S, et al.
Publicado: (1989)

miR‐1254 inhibits progression of glioma in vivo and in vitro by targeting CSF‐1
por: Li, Xin, et al.
Publicado: (2020)

1254. DoD Adherence to CDC Core Elements of Hospital Antibiotic Stewardship Programs
por: Lynch, LeeAnne C, et al.
Publicado: (2023)

DDX17 promotes the growth and metastasis of lung adenocarcinoma
por: Liu, Xiaohui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jhjnspucad29sgq9nevgg8ru0c