Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers

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Neurons depend on proper localization of neurotrophic receptors in their distal processes for their function. The Trk family of neurotrophin receptors controls neuronal survival, differentiation, and remodeling and are well known to function as retrograde signal carriers transported from the distal...

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Detalles Bibliográficos
Autores principales: Zahavi, Eitan Erez, Hummel, Jessica J.A., Han, Yuhao, Bar, Citlali, Stucchi, Riccardo, Altelaar, Maarten, Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907685/
https://www.ncbi.nlm.nih.gov/pubmed/33571451
http://dx.doi.org/10.1016/j.devcel.2021.01.010
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