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Hemistepsin A inhibits T0901317-induced lipogenesis in the liver

Hemistepsin A (HsA) is a guaianolide sesquiterpene lactone that inhibits hepatitis and liver fibrosis. We evaluated the effects of HsA on liver X receptor (LXR)-mediated hepatic lipogenesis in vitro and in vivo. Up to 10 μM, HsA did not affect the viability of HepG2 and Huh7 cells. Pretreatment with...

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Detalles Bibliográficos
Autores principales:	Kim, Jae Kwang, Cho, Il Je, Kim, Eun Ok, Lee, Dae Geon, Jung, Dae Hwa, Ki, Sung Hwan, Ku, Sae Kwang, Kim, Sang Chan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907741/ https://www.ncbi.nlm.nih.gov/pubmed/32843130 http://dx.doi.org/10.5483/BMBRep.2021.54.2.111

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