Cargando…

Pragmatic, double-blind, randomised trial evaluating the impact of red blood cell donor sex on recipient mortality in an academic hospital population: the innovative Trial Assessing Donor Sex (iTADS) protocol

INTRODUCTION: With over 1 million units of blood transfused each year in Canada, their use has a significant clinical and economic impact on our health system. Adequate screening of blood donors is important to ensure the safety and clinical benefit of blood products. Some adverse transfusion reacti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fergusson, Dean A, Chassé, Michael, Tinmouth, Alan, Acker, Jason P, English, Shane, Forster, Alan J, Hawken, Steven, Shehata, Nadine, Thavorn, Kednapa, Wilson, Kumanan, Tuttle, Angie, Perelman, Iris, Cober, Nancy, Maddison, Heather, Tokessy, Melanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Haematology (Incl Blood Transfusion)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907852/ https://www.ncbi.nlm.nih.gov/pubmed/33622960 http://dx.doi.org/10.1136/bmjopen-2021-049598

Ejemplares similares

Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor–recipient continuum
por: Chassé, Michaël, et al.
Publicado: (2015)

Rationale and design of platelet transfusions in haematopoietic stem cell transplantation: the PATH pilot study
por: Tay, Jason, et al.
Publicado: (2016)

Protocol for a modelling study to assess the clinical and cost-effectiveness of indefinite anticoagulant therapy for first unprovoked venous thromboembolism
por: Khan, Faizan, et al.
Publicado: (2023)

Ferritin-guided iron supplementation in whole blood donors: optimal dosage, donor response, return and efficacy (FORTE)—a randomised controlled trial protocol
por: Karregat, Jan, et al.
Publicado: (2022)

Aneurysmal SubArachnoid Hemorrhage—Red Blood Cell Transfusion And Outcome (SAHaRA): a pilot randomised controlled trial protocol
por: English, Shane W, et al.
Publicado: (2016)

Navigating choice in the face of uncertainty: using a theory informed qualitative approach to identifying potential patient barriers and enablers to participating in an early phase chimeric antigen receptor T (CAR-T) cell therapy trial
por: Castillo, Gisell, et al.
Publicado: (2021)

Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients
por: Alshalani, Abdulrahman, et al.
Publicado: (2022)

Views and attitudes towards blood donation: a qualitative investigation of Indian non-donors living in England
por: Joshi, Dhaara, et al.
Publicado: (2017)

Stem cell transplantation of matched sibling donors compared with immunosuppressive therapy for acquired severe aplastic anaemia: a Cochrane systematic review
por: Peinemann, Frank, et al.
Publicado: (2014)

Frequency and distribution of ABO and Rh blood group systems among blood donors at the Northern Zone Blood Transfusion Center in Kilimanjaro, Tanzania: a retrospective cross-sectional study
por: Vuhahula, Edda A M, et al.
Publicado: (2023)

Establishment of sex-specific reference intervals for automated haematology analyser-delivered research parameters in healthy Korean adults: a retrospective database review
por: Jeon, Kibum, et al.
Publicado: (2020)

Efficacy of convalescent plasma therapy in the patient with COVID-19: a randomised control trial (COPLA-II trial)
por: Bajpai, Meenu, et al.
Publicado: (2022)

Trial protocol: a multicentre randomised trial of first-line treatment pathways for newly diagnosed immune thrombocytopenia: standard steroid treatment versus combined steroid and mycophenolate. The FLIGHT trial
por: Pell, Julie, et al.
Publicado: (2018)

Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis
por: Chassé, Michaël, et al.
Publicado: (2014)

Protocol for a multicentre, parallel-group, open-label randomised controlled trial comparing ferric carboxymaltose with the standard of care in anaemic Malawian pregnant women: the REVAMP trial
por: Mwangi, Martin N, et al.
Publicado: (2021)

A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial
por: Ypma, Paula F, et al.
Publicado: (2016)

Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials)
por: Reade, Michael C., et al.
Publicado: (2022)

SWIM (sickle with ibuprofen and morphine) randomised controlled trial fails to recruit: lessons learnt
por: Cho, Gavin, et al.
Publicado: (2016)

Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III trial
por: Coulson, Amy Beth, et al.
Publicado: (2022)

Adaptation of the PERCEPT myeloma prehabilitation trial to virtual delivery: changes in response to the COVID-19 pandemic
por: McCourt, Orla, et al.
Publicado: (2022)

Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol
por: Schünemann, Holger J, et al.
Publicado: (2016)

TILE pilot trial study protocol: Tinzaparin Lead-in to Prevent the Post-Thrombotic syndrome study protocol
por: Makedonov, Ilia, et al.
Publicado: (2023)

Psychometric evaluation of the NTDT-PRO questionnaire for assessing symptoms in patients with non-transfusion-dependent beta-thalassaemia
por: Taher, Ali T, et al.
Publicado: (2023)

Randomised controlled trial of weekly chloroquine to re-establish normal erythron iron flux and haemoglobin recovery in postmalarial anaemia
por: Cox, Sharon E, et al.
Publicado: (2013)

Protocol for a feasibility randomised controlled trial of a musculoskeletal exercise intervention versus usual care for children with haemophilia
por: Hashem, Ferhana, et al.
Publicado: (2019)

Efficacy and safety of oral hydroxyurea in transfusion-dependent β-thalassaemia: a protocol for randomised double-blind controlled clinical trial
por: Yasara, Nirmani, et al.
Publicado: (2020)

Protocol description of the HOVON 141/VISION trial: a prospective, multicentre, randomised phase II trial of ibrutinib plus venetoclax in patients with creatinine clearance ≥30 mL/min who have relapsed or refractory chronic lymphocytic leukaemia (RR-CLL) with or without TP53 aberrations
por: Levin, Mark-David, et al.
Publicado: (2020)

Protocol for updating a systematic review of randomised controlled trials on the prophylactic use of intravenous immunoglobulin for patients undergoing haematopoietic stem cell transplantation
por: Cowan, Juthaporn, et al.
Publicado: (2015)

Reporting conflicts of interest in randomised trials of patient blood management interventions in patients requiring major surgery: a systematic review and meta-analysis
por: Roman, Marius, et al.
Publicado: (2022)

Are survival and mortality rates associated with recruitment to clinical trials in teenage and young adult patients with acute lymphoblastic leukaemia? A retrospective observational analysis in England
por: Hough, Rachael, et al.
Publicado: (2017)

Effectiveness of interventions for the implementation of thromboprophylaxis in hospitalised patients at risk of venous thromboembolism: an updated abridged Cochrane systematic review and meta-analysis of randomised controlled trials
por: Kahn, Susan R, et al.
Publicado: (2019)

Phase 3 randomised trial of eltrombopag versus standard first-line pharmacological management for newly diagnosed immune thrombocytopaenia (ITP) in children: study protocol
por: Shimano, Kristin A, et al.
Publicado: (2021)

Desmopressin treatment combined with clotting factor VIII concentrates in patients with non-severe haemophilia A: protocol for a multicentre single-armed trial, the DAVID study
por: Schütte, Lisette M, et al.
Publicado: (2019)

PERCEPT myeloma: a protocol for a pilot randomised controlled trial of exercise prehabilitation before and during autologous stem cell transplantation in patients with multiple myeloma
por: McCourt, Orla, et al.
Publicado: (2020)

Randomised controlled trial protocol to evaluate a fixed dose prothrombin complex concentrate against the variable dose in vitamin K antagonist related bleeding (PROPER3)
por: Abdoellakhan, Rahat A, et al.
Publicado: (2018)

Is it feasible to conduct a randomised controlled trial of pretransplant exercise (prehabilitation) for patients with multiple myeloma awaiting autologous haematopoietic stem cell transplantation? Protocol for the PREeMPT study
por: Keen, Carol, et al.
Publicado: (2018)

Assessment of global coagulation function under treatment with emicizumab concomitantly with bypassing agents in haemophilia A with inhibitor (UNEBI Study): multicentre open-label non-randomised clinical trial
por: Ogiwara, Kenichi, et al.
Publicado: (2022)

Protocol for a phase III, non-inferiority, randomised comparison of a new fibrinogen concentrate versus cryoprecipitate for treating acquired hypofibrinogenaemia in bleeding cardiac surgical patients: the FIBRES trial
por: Karkouti, Keyvan, et al.
Publicado: (2018)

Faecal microbiota transplantation to prevent complications after allogeneic stem cell transplantation for haematological malignancies: a study protocol for a randomised controlled phase-II trial (the FMT-allo study)
por: Dougé, Aurore, et al.
Publicado: (2023)

Point-of-care washing of allogeneic red blood cells for the prevention of transfusion-related respiratory complications (WAR-PRC): a protocol for a multicenter randomised clinical trial in patients undergoing cardiac surgery
por: Warner, Matthew A, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_g8q0p29n316usnrdfhclt8l970