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Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya
SETTING: Children especially those <5 years of age exposed to pulmonary tuberculosis (TB) are at a high risk of severe TB disease and death. Isoniazid preventive therapy (IPT) has been shown to decrease disease progression by up to 90%. Kenya, a high TB burden country experiences numerous operati...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907885/ https://www.ncbi.nlm.nih.gov/pubmed/33622944 http://dx.doi.org/10.1136/bmjopen-2020-040993 |
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author | Amisi, James A Carter, E Jane Masini, Enos Szkwarko, Daria |
author_facet | Amisi, James A Carter, E Jane Masini, Enos Szkwarko, Daria |
author_sort | Amisi, James A |
collection | PubMed |
description | SETTING: Children especially those <5 years of age exposed to pulmonary tuberculosis (TB) are at a high risk of severe TB disease and death. Isoniazid preventive therapy (IPT) has been shown to decrease disease progression by up to 90%. Kenya, a high TB burden country experiences numerous operational challenges that limit implementation of TB preventive services. IPT completion in child contacts is not routinely reported in Kenya. OBJECTIVE: This study aims to review the child contact management (CCM) cascade and present IPT outcomes across 10 clinics in western Kenya. DESIGN: A retrospective chart review of programmatic data of a TB Reach-funded active, clinic-based CCM strategy. RESULTS: Of 553 child contacts screened, 231 (42%) were reported symptomatic. 74 (13%) of the child contacts were diagnosed with active TB disease. Of those eligible for IPT, 427 (90%) initiated IPT according to TB REACH project data while 249 (58%) were recorded in the IPT register with 49 (11%) recorded as a transfer to other facilities. Of the 249 recorded in the IPT register, 205 (82%) were documented to complete therapy (48% of project initiation children). CONCLUSION: Our evaluation shows gaps in the routine CCM care cascade related to completeness of documentation that require further programmatic monitoring and evaluation to improve CCM outcomes. |
format | Online Article Text |
id | pubmed-7907885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-79078852021-03-09 Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya Amisi, James A Carter, E Jane Masini, Enos Szkwarko, Daria BMJ Open Public Health SETTING: Children especially those <5 years of age exposed to pulmonary tuberculosis (TB) are at a high risk of severe TB disease and death. Isoniazid preventive therapy (IPT) has been shown to decrease disease progression by up to 90%. Kenya, a high TB burden country experiences numerous operational challenges that limit implementation of TB preventive services. IPT completion in child contacts is not routinely reported in Kenya. OBJECTIVE: This study aims to review the child contact management (CCM) cascade and present IPT outcomes across 10 clinics in western Kenya. DESIGN: A retrospective chart review of programmatic data of a TB Reach-funded active, clinic-based CCM strategy. RESULTS: Of 553 child contacts screened, 231 (42%) were reported symptomatic. 74 (13%) of the child contacts were diagnosed with active TB disease. Of those eligible for IPT, 427 (90%) initiated IPT according to TB REACH project data while 249 (58%) were recorded in the IPT register with 49 (11%) recorded as a transfer to other facilities. Of the 249 recorded in the IPT register, 205 (82%) were documented to complete therapy (48% of project initiation children). CONCLUSION: Our evaluation shows gaps in the routine CCM care cascade related to completeness of documentation that require further programmatic monitoring and evaluation to improve CCM outcomes. BMJ Publishing Group 2021-02-23 /pmc/articles/PMC7907885/ /pubmed/33622944 http://dx.doi.org/10.1136/bmjopen-2020-040993 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Public Health Amisi, James A Carter, E Jane Masini, Enos Szkwarko, Daria Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya |
title | Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya |
title_full | Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya |
title_fullStr | Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya |
title_full_unstemmed | Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya |
title_short | Closing the loop in child TB contact management: completion of TB preventive therapy outcomes in western Kenya |
title_sort | closing the loop in child tb contact management: completion of tb preventive therapy outcomes in western kenya |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907885/ https://www.ncbi.nlm.nih.gov/pubmed/33622944 http://dx.doi.org/10.1136/bmjopen-2020-040993 |
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