Cargando…

Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis

Systemic parameters and its relationship with Somatic Cell Count (SCC) in dairy cows were evaluated. Cows that presented subclinical mastitis (SMC; n = 16) and healthy cows (HC; n = 6) were selected and identified by the California Mastitis Test and SCC in milk. SCC results were logarithmically tran...

Descripción completa

Detalles Bibliográficos
Autores principales: Carvalho-Sombra, T.C.F., Fernandes, D.D., Bezerra, B.M.O., Nunes-Pinheiro, D.C.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907891/
https://www.ncbi.nlm.nih.gov/pubmed/33665474
http://dx.doi.org/10.1016/j.vas.2021.100165
_version_ 1783655588821991424
author Carvalho-Sombra, T.C.F.
Fernandes, D.D.
Bezerra, B.M.O.
Nunes-Pinheiro, D.C.S.
author_facet Carvalho-Sombra, T.C.F.
Fernandes, D.D.
Bezerra, B.M.O.
Nunes-Pinheiro, D.C.S.
author_sort Carvalho-Sombra, T.C.F.
collection PubMed
description Systemic parameters and its relationship with Somatic Cell Count (SCC) in dairy cows were evaluated. Cows that presented subclinical mastitis (SMC; n = 16) and healthy cows (HC; n = 6) were selected and identified by the California Mastitis Test and SCC in milk. SCC results were logarithmically transformed into somatic cell score (SCS). HC presented SCS 〈 4.32 while SMC presented SCS 〉 4.32. Milk and blood samples were collected in three days: D1 (first day of sampling), D2 (48 h after D1) and D3 (7 days after D1), to determine White Blood Cells (WBC), albumin, total protein, total bilirubin and malondialdehyde (MDA). Results were expressed as mean ± standard deviation. It was considered significant at P < 0.05. The data of SCS on D1, D2 and D3 in SMC were: 6.8 ± 1.7, 6.4 ± 1.8, and 6.3 ± 2.0, respectively. In SMC the MDA (nmolL(−1)) were: D1 - 9.3 ± 2.6, D2 - 8.6 ± 2.4, and D3 - 11.5 ± 3.5. The MDA on D3 in SMC (11.5 ± 3.5) were increase when compared to HC (6.0 ± 1.3) (P < 0.001). No significant difference was found in WBC, TP, ALB, and TB between groups. It was observed a positive correlation between MDA-SCS (ρ = 0.4) and between WBC-SCS (ρ = 0.3) in the SMC group. It was concluded that the systemic repercussion damage in the mammary gland promoted by subclinical mastitis in dairy cows can be assessed using the MDA and WBC biomarkers.
format Online
Article
Text
id pubmed-7907891
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-79078912021-03-03 Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis Carvalho-Sombra, T.C.F. Fernandes, D.D. Bezerra, B.M.O. Nunes-Pinheiro, D.C.S. Vet Anim Sci Original Article Systemic parameters and its relationship with Somatic Cell Count (SCC) in dairy cows were evaluated. Cows that presented subclinical mastitis (SMC; n = 16) and healthy cows (HC; n = 6) were selected and identified by the California Mastitis Test and SCC in milk. SCC results were logarithmically transformed into somatic cell score (SCS). HC presented SCS 〈 4.32 while SMC presented SCS 〉 4.32. Milk and blood samples were collected in three days: D1 (first day of sampling), D2 (48 h after D1) and D3 (7 days after D1), to determine White Blood Cells (WBC), albumin, total protein, total bilirubin and malondialdehyde (MDA). Results were expressed as mean ± standard deviation. It was considered significant at P < 0.05. The data of SCS on D1, D2 and D3 in SMC were: 6.8 ± 1.7, 6.4 ± 1.8, and 6.3 ± 2.0, respectively. In SMC the MDA (nmolL(−1)) were: D1 - 9.3 ± 2.6, D2 - 8.6 ± 2.4, and D3 - 11.5 ± 3.5. The MDA on D3 in SMC (11.5 ± 3.5) were increase when compared to HC (6.0 ± 1.3) (P < 0.001). No significant difference was found in WBC, TP, ALB, and TB between groups. It was observed a positive correlation between MDA-SCS (ρ = 0.4) and between WBC-SCS (ρ = 0.3) in the SMC group. It was concluded that the systemic repercussion damage in the mammary gland promoted by subclinical mastitis in dairy cows can be assessed using the MDA and WBC biomarkers. Elsevier 2021-01-08 /pmc/articles/PMC7907891/ /pubmed/33665474 http://dx.doi.org/10.1016/j.vas.2021.100165 Text en © 2021 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Carvalho-Sombra, T.C.F.
Fernandes, D.D.
Bezerra, B.M.O.
Nunes-Pinheiro, D.C.S.
Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
title Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
title_full Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
title_fullStr Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
title_full_unstemmed Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
title_short Systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
title_sort systemic inflammatory biomarkers and somatic cell count in dairy cows with subclinical mastitis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907891/
https://www.ncbi.nlm.nih.gov/pubmed/33665474
http://dx.doi.org/10.1016/j.vas.2021.100165
work_keys_str_mv AT carvalhosombratcf systemicinflammatorybiomarkersandsomaticcellcountindairycowswithsubclinicalmastitis
AT fernandesdd systemicinflammatorybiomarkersandsomaticcellcountindairycowswithsubclinicalmastitis
AT bezerrabmo systemicinflammatorybiomarkersandsomaticcellcountindairycowswithsubclinicalmastitis
AT nunespinheirodcs systemicinflammatorybiomarkersandsomaticcellcountindairycowswithsubclinicalmastitis