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Defective autophagy in Sf1 neurons perturbs the metabolic response to fasting and causes mitochondrial dysfunction
OBJECTIVE: The ventromedial nucleus of the hypothalamus (VMH) is a critical component of the forebrain pathways that regulate energy homeostasis. It also plays an important role in the metabolic response to fasting. However, the mechanisms contributing to these physiological processes remain elusive...
Autores principales: | Coupé, Bérengère, Leloup, Corinne, Asiedu, Kwame, Maillard, Julien, Pénicaud, Luc, Horvath, Tamas L., Bouret, Sebastien G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907893/ https://www.ncbi.nlm.nih.gov/pubmed/33571700 http://dx.doi.org/10.1016/j.molmet.2021.101186 |
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