IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells

[Image: see text] Therapeutic immunotoxins composed of antibodies and bacterial toxins provide potent activity against malignant cells, but joining them with a defined covalent bond while maintaining the desired function is challenging. Here, we develop novel immunotoxins by dovetailing full-length...

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Detalles Bibliográficos
Autores principales: Lu, Zeyu, Truex, Nicholas L., Melo, Mariane B., Cheng, Yiran, Li, Na, Irvine, Darrell J., Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908032/
https://www.ncbi.nlm.nih.gov/pubmed/33655074
http://dx.doi.org/10.1021/acscentsci.0c01670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908032/
https://www.ncbi.nlm.nih.gov/pubmed/33655074
http://dx.doi.org/10.1021/acscentsci.0c01670

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