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IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells
[Image: see text] Therapeutic immunotoxins composed of antibodies and bacterial toxins provide potent activity against malignant cells, but joining them with a defined covalent bond while maintaining the desired function is challenging. Here, we develop novel immunotoxins by dovetailing full-length...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908032/ https://www.ncbi.nlm.nih.gov/pubmed/33655074 http://dx.doi.org/10.1021/acscentsci.0c01670 |