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Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population

Aluminum (Al) exposure at human dietary levels raises health concerns, yet little is known about the Al exposure from the Taiwanese diet. The amount of aluminum (Al)-containing food consumption in the Taiwanese total diet is increasing, which contributes to the total diet consumption., which raises...

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Autores principales: You, Shu-Han, Chen, Szu-Chieh, Lin, Chin-Hsin, Chen, Yen-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908212/
https://www.ncbi.nlm.nih.gov/pubmed/33530648
http://dx.doi.org/10.3390/ijerph18031099
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author You, Shu-Han
Chen, Szu-Chieh
Lin, Chin-Hsin
Chen, Yen-Chu
author_facet You, Shu-Han
Chen, Szu-Chieh
Lin, Chin-Hsin
Chen, Yen-Chu
author_sort You, Shu-Han
collection PubMed
description Aluminum (Al) exposure at human dietary levels raises health concerns, yet little is known about the Al exposure from the Taiwanese diet. The amount of aluminum (Al)-containing food consumption in the Taiwanese total diet is increasing, which contributes to the total diet consumption., which raises the health concerns. In this study, we aim to assess estimated weekly intake (EWI) and the percentage of provisional tolerable weekly intake (%PTWI) of the dietary exposure to Al in different age-sex groups. We also applied probabilistic risk analyses to quantify the parameters’ uncertainty by focusing on the distribution function for the Al concentration in food, consumption rate, and body weight in specific age groups. Results indicated that the EWIs declined with increasing age after 6-years old (7–12 > 13–15 > 16–18 > 19–64 > 65+). Results indicated that the EWIs gradually declined after 6-year of age. The EWIs of Al-rich food in cake + waffle, kelp, snacks, and bread contributed 20%, 17%, 17%, and 11%, respectively, to the total EWIs, corresponding with the much higher consumption rates for these four foods. The 75th percentile of EWIs for the children aged 34–6 years had a %PTWI valued at over 100%, indicating a potential risk of Al intake via dietary exposure. Our findings show that there is a concern about the consumption of Al-rich foods for children in Taiwan.
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spelling pubmed-79082122021-02-27 Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population You, Shu-Han Chen, Szu-Chieh Lin, Chin-Hsin Chen, Yen-Chu Int J Environ Res Public Health Article Aluminum (Al) exposure at human dietary levels raises health concerns, yet little is known about the Al exposure from the Taiwanese diet. The amount of aluminum (Al)-containing food consumption in the Taiwanese total diet is increasing, which contributes to the total diet consumption., which raises the health concerns. In this study, we aim to assess estimated weekly intake (EWI) and the percentage of provisional tolerable weekly intake (%PTWI) of the dietary exposure to Al in different age-sex groups. We also applied probabilistic risk analyses to quantify the parameters’ uncertainty by focusing on the distribution function for the Al concentration in food, consumption rate, and body weight in specific age groups. Results indicated that the EWIs declined with increasing age after 6-years old (7–12 > 13–15 > 16–18 > 19–64 > 65+). Results indicated that the EWIs gradually declined after 6-year of age. The EWIs of Al-rich food in cake + waffle, kelp, snacks, and bread contributed 20%, 17%, 17%, and 11%, respectively, to the total EWIs, corresponding with the much higher consumption rates for these four foods. The 75th percentile of EWIs for the children aged 34–6 years had a %PTWI valued at over 100%, indicating a potential risk of Al intake via dietary exposure. Our findings show that there is a concern about the consumption of Al-rich foods for children in Taiwan. MDPI 2021-01-26 2021-02 /pmc/articles/PMC7908212/ /pubmed/33530648 http://dx.doi.org/10.3390/ijerph18031099 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
You, Shu-Han
Chen, Szu-Chieh
Lin, Chin-Hsin
Chen, Yen-Chu
Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population
title Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population
title_full Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population
title_fullStr Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population
title_full_unstemmed Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population
title_short Probabilistic Risk Analysis to Assess Dietary Exposure to Aluminum in the Taiwanese Population
title_sort probabilistic risk analysis to assess dietary exposure to aluminum in the taiwanese population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908212/
https://www.ncbi.nlm.nih.gov/pubmed/33530648
http://dx.doi.org/10.3390/ijerph18031099
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