Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland

In view of previous reports, it is important to determine the relationship between liver function and the level of fluoride in the serum. The aim of this study was to investigate serum concentrations of fluoride in 72 patients with alcoholic liver cirrhosis, living in the region of Lublin (Eastern P...

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Autores principales: Prystupa, Andrzej, Sak, Jarosław, Kiciński, Paweł, Stenzel-Bembenek, Agnieszka, Błażewicz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908415/
https://www.ncbi.nlm.nih.gov/pubmed/33513857
http://dx.doi.org/10.3390/ijerph18031115
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author Prystupa, Andrzej
Sak, Jarosław
Kiciński, Paweł
Stenzel-Bembenek, Agnieszka
Błażewicz, Anna
author_facet Prystupa, Andrzej
Sak, Jarosław
Kiciński, Paweł
Stenzel-Bembenek, Agnieszka
Błażewicz, Anna
author_sort Prystupa, Andrzej
collection PubMed
description In view of previous reports, it is important to determine the relationship between liver function and the level of fluoride in the serum. The aim of this study was to investigate serum concentrations of fluoride in 72 patients with alcoholic liver cirrhosis, living in the region of Lublin (Eastern Poland) divided based on the severity of disease according to the Child-Turcotte-Pugh criteria. Higher plasma fluoride concentrations were associated with changes in liver related parameters. In all groups of analyzed patients with different stages of alcoholic liver cirrhosis, elevated levels of plasma fluoride and increased activities of both alanine aminotransferase (ALT) and total bilirubin concentration were shown.
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spelling pubmed-79084152021-02-27 Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland Prystupa, Andrzej Sak, Jarosław Kiciński, Paweł Stenzel-Bembenek, Agnieszka Błażewicz, Anna Int J Environ Res Public Health Article In view of previous reports, it is important to determine the relationship between liver function and the level of fluoride in the serum. The aim of this study was to investigate serum concentrations of fluoride in 72 patients with alcoholic liver cirrhosis, living in the region of Lublin (Eastern Poland) divided based on the severity of disease according to the Child-Turcotte-Pugh criteria. Higher plasma fluoride concentrations were associated with changes in liver related parameters. In all groups of analyzed patients with different stages of alcoholic liver cirrhosis, elevated levels of plasma fluoride and increased activities of both alanine aminotransferase (ALT) and total bilirubin concentration were shown. MDPI 2021-01-27 2021-02 /pmc/articles/PMC7908415/ /pubmed/33513857 http://dx.doi.org/10.3390/ijerph18031115 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Prystupa, Andrzej
Sak, Jarosław
Kiciński, Paweł
Stenzel-Bembenek, Agnieszka
Błażewicz, Anna
Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland
title Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland
title_full Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland
title_fullStr Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland
title_full_unstemmed Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland
title_short Serum Concentration of Fluoride in Patients with Alcoholic Liver Cirrhosis from the Lublin Region in Eastern Poland
title_sort serum concentration of fluoride in patients with alcoholic liver cirrhosis from the lublin region in eastern poland
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908415/
https://www.ncbi.nlm.nih.gov/pubmed/33513857
http://dx.doi.org/10.3390/ijerph18031115
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