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Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer

AIM: Pemetrexed, a new generation antifolate drug, has been approved for the treatment of locally advanced or metastatic breast cancer. However, factors affecting its efficacy and resistance have not been fully elucidated yet. ATP-binding cassette (ABC) transporters are predictors of prognosis as we...

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Detalles Bibliográficos
Autores principales:	Chen, Jihui, Wang, Zhipeng, Gao, Shouhong, Wu, Kejin, Bai, Fang, Zhang, Qiqiang, Wang, Hongyu, Ye, Qin, Xu, Fengjing, Sun, Hong, Lu, Yunshu, Liu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908708/ https://www.ncbi.nlm.nih.gov/pubmed/33632224 http://dx.doi.org/10.1186/s12935-021-01842-x

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