Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report

We present a case where nitroglycerin tablets dissolved in saline and intravenous nitroglycerin solution were nebulized as surrogates for inhaled nitric oxide (iNO) after our iNO supply was depleted during the coronavirus disease 2019 (COVID-19) surge in New York. We gave this treatment to a COVID-1...

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Detalles Bibliográficos
Autores principales: Daxon, Benjamin T., Lark, Erin, Matzek, Luke J., Fields, Amanda R., Haselton, Kyle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908862/
https://www.ncbi.nlm.nih.gov/pubmed/33560642
http://dx.doi.org/10.1213/XAA.0000000000001376
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author Daxon, Benjamin T.
Lark, Erin
Matzek, Luke J.
Fields, Amanda R.
Haselton, Kyle J.
author_facet Daxon, Benjamin T.
Lark, Erin
Matzek, Luke J.
Fields, Amanda R.
Haselton, Kyle J.
author_sort Daxon, Benjamin T.
collection PubMed
description We present a case where nitroglycerin tablets dissolved in saline and intravenous nitroglycerin solution were nebulized as surrogates for inhaled nitric oxide (iNO) after our iNO supply was depleted during the coronavirus disease 2019 (COVID-19) surge in New York. We gave this treatment to a COVID-19 patient with severe acute respiratory distress syndrome (ARDS) and hypercarbia. In response, the patient had immediate and clinically meaningful improvement in multiple organ systems despite no other interventions or ventilator changes.
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spelling pubmed-79088622021-03-01 Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report Daxon, Benjamin T. Lark, Erin Matzek, Luke J. Fields, Amanda R. Haselton, Kyle J. A A Pract Case Report We present a case where nitroglycerin tablets dissolved in saline and intravenous nitroglycerin solution were nebulized as surrogates for inhaled nitric oxide (iNO) after our iNO supply was depleted during the coronavirus disease 2019 (COVID-19) surge in New York. We gave this treatment to a COVID-19 patient with severe acute respiratory distress syndrome (ARDS) and hypercarbia. In response, the patient had immediate and clinically meaningful improvement in multiple organ systems despite no other interventions or ventilator changes. Lippincott Williams & Wilkins 2021-02-05 /pmc/articles/PMC7908862/ /pubmed/33560642 http://dx.doi.org/10.1213/XAA.0000000000001376 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Anesthesia Research Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Case Report
Daxon, Benjamin T.
Lark, Erin
Matzek, Luke J.
Fields, Amanda R.
Haselton, Kyle J.
Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report
title Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report
title_full Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report
title_fullStr Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report
title_full_unstemmed Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report
title_short Nebulized Nitroglycerin for Coronavirus Disease 2019–Associated Acute Respiratory Distress Syndrome: A Case Report
title_sort nebulized nitroglycerin for coronavirus disease 2019–associated acute respiratory distress syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7908862/
https://www.ncbi.nlm.nih.gov/pubmed/33560642
http://dx.doi.org/10.1213/XAA.0000000000001376
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