The impact of baseline brain metastases on clinical benefits and progression patterns after first-line crizotinib in anaplastic lymphoma kinase-rearranged non-small cell lung cancer

Baseline brain metastasis (BBM) commonly occurs in anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer. Crizotinib prolongs the survival of patients with ALK rearrangement but lacks significant effect on brain metastasis. It remains unclear whether BBM and local therapy affect the...

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Detalles Bibliográficos
Autores principales: Chen, Yuqi, Cai, Chengzhi, Li, Yanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909142/
https://www.ncbi.nlm.nih.gov/pubmed/33663095
http://dx.doi.org/10.1097/MD.0000000000024784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909142/
https://www.ncbi.nlm.nih.gov/pubmed/33663095
http://dx.doi.org/10.1097/MD.0000000000024784

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