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Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography

Background: Traditionally, fat mass is estimated using anthropometric models. Air-displacement plethysmography (ADP) is a relatively new technique for determining fat mass. There is limited information on the agreement between these methods in infants and young children. Therefore we aimed to longit...

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Autores principales: Kouwenhoven, Stefanie M. P., Antl, Nadja, Twisk, Jos W. R., Koletzko, Berthold V., Finken, Martijn J. J., van Goudoever, Johannes B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909249/
https://www.ncbi.nlm.nih.gov/pubmed/33498272
http://dx.doi.org/10.3390/life11020075
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author Kouwenhoven, Stefanie M. P.
Antl, Nadja
Twisk, Jos W. R.
Koletzko, Berthold V.
Finken, Martijn J. J.
van Goudoever, Johannes B.
author_facet Kouwenhoven, Stefanie M. P.
Antl, Nadja
Twisk, Jos W. R.
Koletzko, Berthold V.
Finken, Martijn J. J.
van Goudoever, Johannes B.
author_sort Kouwenhoven, Stefanie M. P.
collection PubMed
description Background: Traditionally, fat mass is estimated using anthropometric models. Air-displacement plethysmography (ADP) is a relatively new technique for determining fat mass. There is limited information on the agreement between these methods in infants and young children. Therefore we aimed to longitudinally compare fat mass percentage values predicted from skinfold thicknesses (SFTs) and ADP in healthy infants and young children. Methods: Anthropometry and body composition were determined at the ages of 1, 4, and 6 months and 2 years. We quantified the agreement between the two methods using the Bland–Altman procedure, linear mixed-model analysis, and intra-class correlation coefficients (ICC). Results: During the first 6 months of life, fat mass% predicted with SFT was significantly different from that measured with ADP in healthy, term-born infants (n = 245). ICCs ranged from 0.33 (at 2 years of age) and 0.47 (at 4 months of age). Although the mean difference (bias) between the methods was low, the Bland–Altman plots showed proportional differences at all ages with wide limits of agreement. Conclusions: There is poor agreement between ADP and SFTs for estimating fat mass in infancy or early childhood. The amount of body fat was found to influence the agreement between the methods.
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spelling pubmed-79092492021-02-27 Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography Kouwenhoven, Stefanie M. P. Antl, Nadja Twisk, Jos W. R. Koletzko, Berthold V. Finken, Martijn J. J. van Goudoever, Johannes B. Life (Basel) Article Background: Traditionally, fat mass is estimated using anthropometric models. Air-displacement plethysmography (ADP) is a relatively new technique for determining fat mass. There is limited information on the agreement between these methods in infants and young children. Therefore we aimed to longitudinally compare fat mass percentage values predicted from skinfold thicknesses (SFTs) and ADP in healthy infants and young children. Methods: Anthropometry and body composition were determined at the ages of 1, 4, and 6 months and 2 years. We quantified the agreement between the two methods using the Bland–Altman procedure, linear mixed-model analysis, and intra-class correlation coefficients (ICC). Results: During the first 6 months of life, fat mass% predicted with SFT was significantly different from that measured with ADP in healthy, term-born infants (n = 245). ICCs ranged from 0.33 (at 2 years of age) and 0.47 (at 4 months of age). Although the mean difference (bias) between the methods was low, the Bland–Altman plots showed proportional differences at all ages with wide limits of agreement. Conclusions: There is poor agreement between ADP and SFTs for estimating fat mass in infancy or early childhood. The amount of body fat was found to influence the agreement between the methods. MDPI 2021-01-20 /pmc/articles/PMC7909249/ /pubmed/33498272 http://dx.doi.org/10.3390/life11020075 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kouwenhoven, Stefanie M. P.
Antl, Nadja
Twisk, Jos W. R.
Koletzko, Berthold V.
Finken, Martijn J. J.
van Goudoever, Johannes B.
Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
title Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
title_full Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
title_fullStr Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
title_full_unstemmed Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
title_short Methods to Assess Fat Mass in Infants and Young Children: A Comparative Study Using Skinfold Thickness and Air-Displacement Plethysmography
title_sort methods to assess fat mass in infants and young children: a comparative study using skinfold thickness and air-displacement plethysmography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909249/
https://www.ncbi.nlm.nih.gov/pubmed/33498272
http://dx.doi.org/10.3390/life11020075
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