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Impaired Alignment of Bone Matrix Microstructure Associated with Disorganized Osteoblast Arrangement in Malignant Melanoma Metastasis
Malignant melanoma favors spreading to bone, resulting in a weakened bone with a high fracture risk. Here, we revealed the disorganized alignment of apatite crystals in the bone matrix associated with the homing of cancer cells by developing an artificially controlled ex vivo melanoma bone metastasi...
Autores principales: | Matsugaki, Aira, Kimura, Yumi, Watanabe, Ryota, Nakamura, Fumihito, Takehana, Ryo, Nakano, Takayoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909255/ https://www.ncbi.nlm.nih.gov/pubmed/33498283 http://dx.doi.org/10.3390/biom11020131 |
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