Cargando…

Deoxynivalenol Induces Caspase-8-Mediated Apoptosis through the Mitochondrial Pathway in Hippocampal Nerve Cells of Piglet

Deoxynivalenol (DON) is a common trichothecene mycotoxin found worldwide. DON has broad toxicity towards animals and humans. However, the mechanism of DON-induced neurotoxicity in vitro has not been fully understood. This study investigated the hypothesis that DON toxicity in neurons occurs via the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Li, Jiang, Yunjing, Zhu, Lei, Xu, Wei, Chu, Xiaoyan, Zhang, Yafei, Rahman, Sajid Ur, Feng, Shibin, Li, Yu, Wu, Jinjie, Wang, Xichun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909276/ https://www.ncbi.nlm.nih.gov/pubmed/33498252 http://dx.doi.org/10.3390/toxins13020073

Ejemplares similares

Combination of Zearalenone and Deoxynivalenol Induces Apoptosis by Mitochondrial Pathway in Piglet Sertoli Cells: Role of Endoplasmic Reticulum Stress
por: Hai, Sirao, et al.
Publicado: (2023)

Deoxynivalenol Induces Inflammatory Injury in IPEC-J2 Cells via NF-κB Signaling Pathway
por: Wang, Xichun, et al.
Publicado: (2019)

Prevalence of Caprine brucellosis in Anhui province, China
por: Rahman, Sajid Ur, et al.
Publicado: (2019)

Inhibition of Mitochondrial Fission Alleviates Zearalenone-Induced Mitochondria-Associated Endoplasmic Reticulum Membrane Dysfunction in Piglet Sertoli Cells
por: Ma, Li, et al.
Publicado: (2023)

Tea polyphenols attenuate liver inflammation by modulating obesity-related genes and down-regulating COX-2 and iNOS expression in high fat-fed dogs
por: Rahman, Sajid Ur, et al.
Publicado: (2020)

Zearalenone Induces Apoptosis in Porcine Endometrial Stromal Cells through JNK Signaling Pathway Based on Endoplasmic Reticulum Stress
por: Zhao, Jie, et al.
Publicado: (2022)

Deoxynivalenol Induces Intestinal Damage and Inflammatory Response through the Nuclear Factor-κB Signaling Pathway in Piglets
por: Wang, Xi-Chun, et al.
Publicado: (2019)

Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF-κB/MAPK Signaling Pathway
por: Li, Yu, et al.
Publicado: (2017)

Therapeutic Role of Green Tea Polyphenols in Improving Fertility: A Review
por: Rahman, Sajid Ur, et al.
Publicado: (2018)

Therapeutic Effects of Glutamic Acid in Piglets Challenged with Deoxynivalenol
por: Wu, Miaomiao, et al.
Publicado: (2014)

Soybean Antigen Protein-Induced Intestinal Barrier Damage by Trigging Endoplasmic Reticulum Stress and Disordering Gut Microbiota in Weaned Piglets
por: Wang, Lei, et al.
Publicado: (2023)

Resveratrol Improves Intestinal Morphology and Anti-Oxidation Ability in Deoxynivalenol-Challenged Piglets
por: Hong, Qihua, et al.
Publicado: (2022)

Chloroquine Improves Deoxynivalenol-Induced Inflammatory Response and Intestinal Mucosal Damage in Piglets
por: Liao, Simeng, et al.
Publicado: (2020)

Transmission of Zearalenone, Deoxynivalenol, and Their Derivatives from Sows to Piglets during Lactation
por: Benthem de Grave, Xandra, et al.
Publicado: (2021)

Deoxynivalenol- and zearalenone-contaminated feeds alter gene expression profiles in the livers of piglets
por: Reddy, Kondreddy Eswar, et al.
Publicado: (2018)

Effects of deoxynivalenol- and zearalenone-contaminated feed on the gene expression profiles in the kidneys of piglets
por: Reddy, Kondreddy Eswar, et al.
Publicado: (2018)

The Evaluation of the Antioxidant and Intestinal Protective Effects of Baicalin-Copper in Deoxynivalenol-Challenged Piglets
por: Zha, Andong, et al.
Publicado: (2020)

Rutin Supplementation Reduces Oxidative Stress, Inflammation and Apoptosis of Mammary Gland in Sheep During the Transition Period
por: Ding, Hongyan, et al.
Publicado: (2022)

Observations on biotic parameters of Angora rabbit breed under controlled conditions in different housing systems
por: Rahman, Sajid Ur, et al.
Publicado: (2018)

An NMR-Based Metabolomic Approach to Investigate the Effects of Supplementation with Glutamic Acid in Piglets Challenged with Deoxynivalenol
por: Wu, Miaomiao, et al.
Publicado: (2014)

Effect of fosfomycin, Cynara scolymus extract, deoxynivalenol and their combinations on intestinal health of weaned piglets
por: Martínez, Guadalupe, et al.
Publicado: (2019)

Effect of Resveratrol Supplementation on Intestinal Oxidative Stress, Immunity and Gut Microbiota in Weaned Piglets Challenged with Deoxynivalenol
por: Qiu, Yueqin, et al.
Publicado: (2022)

Deoxynivalenol (DON) Contamination of Feed and Grinding Fineness: Are There Interactive Implications on Stomach Integrity and Health of Piglets?
por: Dänicke, Sven, et al.
Publicado: (2017)

Maternal Exposure Results in Long-Term Deoxynivalenol Persistence in Piglets’ Plasma and Modulates the Immune System
por: Štěpánová, Hana, et al.
Publicado: (2020)

Metaproteomics Reveals Alteration of the Gut Microbiome in Weaned Piglets Due to the Ingestion of the Mycotoxins Deoxynivalenol and Zearalenone
por: Saenz, Johan S., et al.
Publicado: (2021)

Baicalin–Zinc Complex Alleviates Inflammatory Responses and Hormone Profiles by Microbiome in Deoxynivalenol Induced Piglets
por: Zha, Andong, et al.
Publicado: (2021)

Cytochrome P450 enzymes mediated by DNA methylation is involved in deoxynivalenol-induced hepatoxicity in piglets
por: Liu, Aimei, et al.
Publicado: (2022)

Control of Mitochondrial Dynamics by Fas-induced Caspase-8 Activation in Hippocampal Neurons
por: Cho, Hyo Min, et al.
Publicado: (2015)

Deoxynivalenol Impairs Porcine Intestinal Host Defense Peptide Expression in Weaned Piglets and IPEC-J2 Cells
por: Wang, Shuai, et al.
Publicado: (2018)

Deoxynivalenol Inhibits Porcine Intestinal Trefoil Factors Expression in Weanling Piglets and IPEC-J2 Cells
por: Wang, Shuai, et al.
Publicado: (2019)

Glycyrrhizic Acid and Compound Probiotics Supplementation Alters the Intestinal Transcriptome and Microbiome of Weaned Piglets Exposed to Deoxynivalenol
por: Xu, Xiaoxiang, et al.
Publicado: (2022)

Neurotoxic Potential of Deoxynivalenol in Murine Brain Cell Lines and Primary Hippocampal Cultures
por: Fæste, Christiane Kruse, et al.
Publicado: (2022)

Dietary resveratrol attenuation of intestinal inflammation and oxidative damage is linked to the alteration of gut microbiota and butyrate in piglets challenged with deoxynivalenol
por: Qiu, Yueqin, et al.
Publicado: (2021)

Lycopene Maintains Mitochondrial Homeostasis to Counteract the Enterotoxicity of Deoxynivalenol
por: Cai, Zihui, et al.
Publicado: (2023)

Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway
por: Li, Yu, et al.
Publicado: (2020)

Corrigendum: Non-esterified Fatty Acid Induce Dairy Cow Hepatocytes Apoptosis via the Mitochondria-Mediated ROS-JNK/ERK Signaling Pathway
por: Li, Yu, et al.
Publicado: (2020)

Mitochondrial damage in hippocampal neurons of rats with epileptic protein expression of Fas and caspase-3
por: Feng, Junqiang, et al.
Publicado: (2018)

Apoptosis induced by acrylamide is suppressed in a 21.5% fat diet through caspase-3-independent pathway in mice testis
por: Zhang, Xichun, et al.
Publicado: (2009)

Conversion of Deoxynivalenol-3-Glucoside to Deoxynivalenol during Chinese Steamed Bread Processing
por: Zhang, Huijie, et al.
Publicado: (2020)

Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets
por: Mikami, Osamu, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ds5cjfnufbmr2m7926gv70eph2