An update on the role of long non-coding RNAs in psoriasis

Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and...

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Autores principales: Song, Jian-Kun, Yin, Shuang-Yi, Li, Wei, Li, Xiao-Dong, Luo, Yue, Luo, Ying, Xing, Meng, Li, Bin, Kuai, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909295/
https://www.ncbi.nlm.nih.gov/pubmed/33323820
http://dx.doi.org/10.1097/CM9.0000000000001243
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author Song, Jian-Kun
Yin, Shuang-Yi
Li, Wei
Li, Xiao-Dong
Luo, Yue
Luo, Ying
Xing, Meng
Li, Bin
Kuai, Le
author_facet Song, Jian-Kun
Yin, Shuang-Yi
Li, Wei
Li, Xiao-Dong
Luo, Yue
Luo, Ying
Xing, Meng
Li, Bin
Kuai, Le
author_sort Song, Jian-Kun
collection PubMed
description Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells.
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spelling pubmed-79092952021-03-01 An update on the role of long non-coding RNAs in psoriasis Song, Jian-Kun Yin, Shuang-Yi Li, Wei Li, Xiao-Dong Luo, Yue Luo, Ying Xing, Meng Li, Bin Kuai, Le Chin Med J (Engl) Review Article Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational levels; however, the specific regulatory mechanisms of lncRNAs in psoriasis remain largely unexplored. This review provides an overview of recent studies investigating mechanisms and functions of lncRNAs in psoriasis, especially focusing on the role of lncRNAs in keratinocytes, T cells, and dendritic cells. Lippincott Williams & Wilkins 2021-02-20 2020-12-11 /pmc/articles/PMC7909295/ /pubmed/33323820 http://dx.doi.org/10.1097/CM9.0000000000001243 Text en Copyright © 2021 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Review Article
Song, Jian-Kun
Yin, Shuang-Yi
Li, Wei
Li, Xiao-Dong
Luo, Yue
Luo, Ying
Xing, Meng
Li, Bin
Kuai, Le
An update on the role of long non-coding RNAs in psoriasis
title An update on the role of long non-coding RNAs in psoriasis
title_full An update on the role of long non-coding RNAs in psoriasis
title_fullStr An update on the role of long non-coding RNAs in psoriasis
title_full_unstemmed An update on the role of long non-coding RNAs in psoriasis
title_short An update on the role of long non-coding RNAs in psoriasis
title_sort update on the role of long non-coding rnas in psoriasis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909295/
https://www.ncbi.nlm.nih.gov/pubmed/33323820
http://dx.doi.org/10.1097/CM9.0000000000001243
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