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Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology

Essential oils are used in an increasing number of applications including biopesticides. Their volatility minimizes the risk of residue but can also be a constraint if the release is rapid and uncontrolled. Solutions allowing the encapsulation of essential oils are therefore strongly researched. In...

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Autores principales: Maes, Chloë, Brostaux, Yves, Bouquillon, Sandrine, Fauconnier, Marie-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909450/
https://www.ncbi.nlm.nih.gov/pubmed/33498387
http://dx.doi.org/10.3390/foods10020207
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author Maes, Chloë
Brostaux, Yves
Bouquillon, Sandrine
Fauconnier, Marie-Laure
author_facet Maes, Chloë
Brostaux, Yves
Bouquillon, Sandrine
Fauconnier, Marie-Laure
author_sort Maes, Chloë
collection PubMed
description Essential oils are used in an increasing number of applications including biopesticides. Their volatility minimizes the risk of residue but can also be a constraint if the release is rapid and uncontrolled. Solutions allowing the encapsulation of essential oils are therefore strongly researched. In this study, essential oils encapsulation was carried out within dendrimers to control their volatility. Indeed, a spontaneous complexation occurs in a solution of dendrimers with essential oils which maintains it longer. Six parameters (temperature, stirring rate, relative concentration, solvent volume, stirring time, and pH) of this reaction has been optimized by two steps: first a screening of the parameters that influence the encapsulation with a Plackett–Burmann design the most followed by an optimization of those ones by a surface response methodology. In this study, two essential oils with herbicide properties were used: the essential oils of Cinnamomum zeylanicum Blume and Cymbopogon winterianus Jowitt; and four biosourced dendrimers: glycerodendrimers derived from polypropylenimine and polyamidoamine, a glyceroclikdendrimer, and a glyceroladendrimer. Meta-analysis of all Plackett–Burman assays determined that rate and stirring time were effective on the retention rate thereby these parameters were used for the surface response methodology part. Each combination gives a different optimum depending on the structure of these molecules.
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spelling pubmed-79094502021-02-27 Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology Maes, Chloë Brostaux, Yves Bouquillon, Sandrine Fauconnier, Marie-Laure Foods Article Essential oils are used in an increasing number of applications including biopesticides. Their volatility minimizes the risk of residue but can also be a constraint if the release is rapid and uncontrolled. Solutions allowing the encapsulation of essential oils are therefore strongly researched. In this study, essential oils encapsulation was carried out within dendrimers to control their volatility. Indeed, a spontaneous complexation occurs in a solution of dendrimers with essential oils which maintains it longer. Six parameters (temperature, stirring rate, relative concentration, solvent volume, stirring time, and pH) of this reaction has been optimized by two steps: first a screening of the parameters that influence the encapsulation with a Plackett–Burmann design the most followed by an optimization of those ones by a surface response methodology. In this study, two essential oils with herbicide properties were used: the essential oils of Cinnamomum zeylanicum Blume and Cymbopogon winterianus Jowitt; and four biosourced dendrimers: glycerodendrimers derived from polypropylenimine and polyamidoamine, a glyceroclikdendrimer, and a glyceroladendrimer. Meta-analysis of all Plackett–Burman assays determined that rate and stirring time were effective on the retention rate thereby these parameters were used for the surface response methodology part. Each combination gives a different optimum depending on the structure of these molecules. MDPI 2021-01-20 /pmc/articles/PMC7909450/ /pubmed/33498387 http://dx.doi.org/10.3390/foods10020207 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Maes, Chloë
Brostaux, Yves
Bouquillon, Sandrine
Fauconnier, Marie-Laure
Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology
title Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology
title_full Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology
title_fullStr Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology
title_full_unstemmed Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology
title_short Use of New Glycerol-Based Dendrimers for Essential Oils Encapsulation: Optimization of Stirring Time and Rate Using a Plackett—Burman Design and a Surface Response Methodology
title_sort use of new glycerol-based dendrimers for essential oils encapsulation: optimization of stirring time and rate using a plackett—burman design and a surface response methodology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909450/
https://www.ncbi.nlm.nih.gov/pubmed/33498387
http://dx.doi.org/10.3390/foods10020207
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