Cargando…

Splicing Genomics Events in Cervical Cancer: Insights for Phenotypic Stratification and Biomarker Potency

Gynaecological cancers are attributed to the second most diagnosed cancers in women after breast cancer. On a global scale, cervical cancer is the fourth most common cancer and the most common cancer in developing countries with rapidly increasing mortality rates. Human papillomavirus (HPV) infectio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Francies, Flavia Zita, Bassa, Sheynaz, Chatziioannou, Aristotelis, Kaufmann, Andreas Martin, Dlamini, Zodwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909518/ https://www.ncbi.nlm.nih.gov/pubmed/33498485 http://dx.doi.org/10.3390/genes12020130

Ejemplares similares

Aberrant Splicing Events and Epigenetics in Viral Oncogenomics: Current Therapeutic Strategies
por: Francies, Flavia Zita, et al.
Publicado: (2021)

Colorectal Cancer Genetics, Incidence and Risk Factors: In Search for Targeted Therapies
por: Hull, Rodney, et al.
Publicado: (2020)

Artificial intelligence (AI) and big data in cancer and precision oncology
por: Dlamini, Zodwa, et al.
Publicado: (2020)

MicroRNA and Alternative mRNA Splicing Events in Cancer Drug Response/Resistance: Potent Therapeutic Targets
por: Marima, Rahaba, et al.
Publicado: (2021)

Genetic Drivers of Head and Neck Squamous Cell Carcinoma: Aberrant Splicing Events, Mutational Burden, HPV Infection and Future Targets
por: Dlamini, Zodwa, et al.
Publicado: (2021)

Prognostic Alternative Splicing Signatures in Esophageal Carcinoma
por: Dlamini, Zodwa, et al.
Publicado: (2021)

The Catastrophic HPV/HIV Dual Viral Oncogenomics in Concert with Dysregulated Alternative Splicing in Cervical Cancer
por: Marima, Rahaba, et al.
Publicado: (2021)

Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities
por: Basera, Afra, et al.
Publicado: (2022)

Can the HIV-1 splicing machinery be targeted for drug discovery?
por: Dlamini, Zodwa, et al.
Publicado: (2017)

The role played by alternative splicing in antigenic variability in human endo-parasites
por: Hull, Rodney, et al.
Publicado: (2014)

Abnormalities in Alternative Splicing of Apoptotic Genes and Cardiovascular Diseases
por: Dlamini, Zodwa, et al.
Publicado: (2015)

Immunosuppressive Signaling Pathways as Targeted Cancer Therapies
por: Setlai, Botle Precious, et al.
Publicado: (2022)

Regulation of alternative splicing in obesity-induced hypertension
por: Dlamini, Zodwa, et al.
Publicado: (2019)

Alternative Splicing Events and Their Clinical Significance in Colorectal Cancer: Targeted Therapeutic Opportunities
por: Manabile, Mosebo Armstrong, et al.
Publicado: (2023)

Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers
por: Mthembu, Nonkululeko N, et al.
Publicado: (2017)

Immunomodulatory Gene-Splicing Dysregulation in Tumorigenesis: Unmasking the Complexity
por: Maebele, Lorraine Tshegofatso, et al.
Publicado: (2023)

RBBP6 Is Abundantly Expressed in Human Cervical Carcinoma and May Be Implicated in Its Malignant Progression
por: Dlamini, Zodwa, et al.
Publicado: (2019)

Microbiomes, Epigenomics, Immune Response, and Splicing Signatures Interplay: Potential Use of Combination of Regulatory Pathways as Targets for Malignant Mesothelioma
por: Setlai, Botle Precious, et al.
Publicado: (2022)

Exploiting the Molecular Basis of Oesophageal Cancer for Targeted Therapies and Biomarkers for Drug Response: Guiding Clinical Decision-Making
por: Mbatha, Sikhumbuzo, et al.
Publicado: (2022)

Prostate Cancer Disparities and Management in Southern Africa: Insights into Practices, Norms and Values
por: Marima, Rahaba, et al.
Publicado: (2022)

Editorial: Cholesterol and cancer drug resistance: Molecular, signaling, and therapeutic aspects
por: Kaur, Mandeep, et al.
Publicado: (2022)

Translocator Protein (TSPO) as a Potential Biomarker in Human Cancers
por: Bhoola, Nimisha H., et al.
Publicado: (2018)

An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes
por: Hicks, Chindo, et al.
Publicado: (2017)

Many Voices in a Choir: Tumor-Induced Neurogenesis and Neuronal Driven Alternative Splicing Sound Like Suspects in Tumor Growth and Dissemination
por: Dlamini, Zodwa, et al.
Publicado: (2021)

GWAS meta-analyses clarify the genetics of cervical phenotypes and inform risk stratification for cervical cancer
por: Koel, Mariann, et al.
Publicado: (2023)

Human Immunodeficiency Virus-1 (HIV-1)-Mediated Apoptosis: New Therapeutic Targets
por: Mbita, Zukile, et al.
Publicado: (2014)

LncRNAs and the Angiogenic Switch in Cancer: Clinical Significance and Therapeutic Opportunities
por: Mabeta, Peace, et al.
Publicado: (2022)

Apoptosis in Cancer Cells Is Induced by Alternative Splicing of hnRNPA2/B1 Through Splicing of Bcl-x, a Mechanism that Can Be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata
por: Makhafola, Tshepiso Jan, et al.
Publicado: (2020)

HIV-Associated Cancer Biomarkers: A Requirement for Early Diagnosis
por: Dlamini, Zodwa, et al.
Publicado: (2021)

The Role of MicroRNAs in Kidney Disease
por: Mukhadi, Sydwell, et al.
Publicado: (2015)

Esophageal cancer genetics in South Africa
por: Alaouna, Mohammed, et al.
Publicado: (2019)

Efavirenz induces DNA damage response pathway in lung cancer
por: Marima, Rahaba, et al.
Publicado: (2020)

Efavirenz and Lopinavir/Ritonavir Alter Cell Cycle Regulation in Lung Cancer
por: Marima, Rahaba, et al.
Publicado: (2020)

The profiling, identification, quantification and analysis of differentially expressed genes (DEGs) in response to drug treatment in lung cancer
por: Marima, Rahaba, et al.
Publicado: (2021)

Role and Merits of Green Based Nanocarriers in Cancer Treatment
por: Elbagory, Abdulrahman M., et al.
Publicado: (2021)

Cervical cancer in low and middle-income countries
por: Hull, Rodney, et al.
Publicado: (2020)

Palmitic acid conjugation enhances potency of tricyclo-DNA splice switching oligonucleotides
por: Relizani, Karima, et al.
Publicado: (2021)

Integration of High-Volume Molecular and Imaging Data for Composite Biomarker Discovery in the Study of Melanoma
por: Moutselos, Konstantinos, et al.
Publicado: (2014)

Reports of Plant-Derived Nanoparticles for Prostate Cancer Therapy
por: Elbagory, Abdulrahman M., et al.
Publicado: (2023)

Insights into the Influence of Specific Splicing Events on the Structural Organization of LRRK2
por: Vlachakis, Dimitrios, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3iaorf35mqlq35rr87s28hl6lv