Unique Cellular and Biochemical Features of Human Mitochondrial Peroxiredoxin 3 Establish the Molecular Basis for Its Specific Reaction with Thiostrepton

A central hallmark of tumorigenesis is metabolic alterations that increase mitochondrial reactive oxygen species (mROS). In response, cancer cells upregulate their antioxidant capacity and redox-responsive signaling pathways. A promising chemotherapeutic approach is to increase ROS to levels incompa...

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Detalles Bibliográficos
Autores principales: Nelson, Kimberly J., Messier, Terri, Milczarek, Stephanie, Saaman, Alexis, Beuschel, Stacie, Gandhi, Uma, Heintz, Nicholas, Smalley, Terrence L., Lowther, W. Todd, Cunniff, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909569/
https://www.ncbi.nlm.nih.gov/pubmed/33498547
http://dx.doi.org/10.3390/antiox10020150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909569/
https://www.ncbi.nlm.nih.gov/pubmed/33498547
http://dx.doi.org/10.3390/antiox10020150

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