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LRRK2 Modulates the Exocyst Complex Assembly by Interacting with Sec8
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson’s disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in the control of vesicle trafficking, likely by Rab p...
Autores principales: | Fais, Milena, Sanna, Giovanna, Galioto, Manuela, Nguyen, Thi Thanh Duyen, Trần, Mai Uyên Thi, Sini, Paola, Carta, Franco, Turrini, Franco, Xiong, Yulan, Dawson, Ted M., Dawson, Valina L., Crosio, Claudia, Iaccarino, Ciro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909581/ https://www.ncbi.nlm.nih.gov/pubmed/33498474 http://dx.doi.org/10.3390/cells10020203 |
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