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Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria

Avian hepatitis E virus (aHEV) is associated with hepatitis-splenomegaly syndrome, big liver and spleen disease and hepatic rupture haemorrhage syndrome. However, the knowledge about aHEV in commercial layer chickens in Nigeria is scarce. In this study, 460 serum samples obtained from 36 apparently...

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Autores principales: Osamudiamen, Fisayo Temilade, Akanbi, Olusola Aanuoluwapo, Oluwayelu, Daniel Oladimeji, Bock, C. -Thomas, Klink, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909675/
https://www.ncbi.nlm.nih.gov/pubmed/33635917
http://dx.doi.org/10.1371/journal.pone.0247889
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author Osamudiamen, Fisayo Temilade
Akanbi, Olusola Aanuoluwapo
Oluwayelu, Daniel Oladimeji
Bock, C. -Thomas
Klink, Patrycja
author_facet Osamudiamen, Fisayo Temilade
Akanbi, Olusola Aanuoluwapo
Oluwayelu, Daniel Oladimeji
Bock, C. -Thomas
Klink, Patrycja
author_sort Osamudiamen, Fisayo Temilade
collection PubMed
description Avian hepatitis E virus (aHEV) is associated with hepatitis-splenomegaly syndrome, big liver and spleen disease and hepatic rupture haemorrhage syndrome. However, the knowledge about aHEV in commercial layer chickens in Nigeria is scarce. In this study, 460 serum samples obtained from 36 apparently healthy commercial layer chicken flocks in three states (Ogun, Osun and Oyo States) of southwestern Nigeria were analysed by enzyme linked immunosorbent assay for the presence of anti-aHEV immunoglobulin Y (IgY) antibodies. In total, the overall seroprevalence of anti-aHEV antibodies was 14.6%. The serological analysis revealed that 75% of the flocks examined were positive for anti-aHEV IgY antibodies from chickens of various ages in all three states. The percentage of the seropositive chickens in the three states varied from flock to flock ranging from 60% to 88.8% and seropositive chickens were detected at any age (24–52 weeks of age) without significant differences between the age groups. This is the first report assessing the presence of aHEV antibodies in chickens from Nigeria. The detection of anti-aHEV antibodies in commercial layer chickens in this study emphasizes the importance of serosurveillance in disease monitoring due to the economic threat posed by aHEV as a result of decreased egg production and increased mortality in affected commercial layer chicken farms. However, further studies are essential to reveal the clinical implications and to assess the real burden of aHEV in Nigeria.
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spelling pubmed-79096752021-03-05 Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria Osamudiamen, Fisayo Temilade Akanbi, Olusola Aanuoluwapo Oluwayelu, Daniel Oladimeji Bock, C. -Thomas Klink, Patrycja PLoS One Research Article Avian hepatitis E virus (aHEV) is associated with hepatitis-splenomegaly syndrome, big liver and spleen disease and hepatic rupture haemorrhage syndrome. However, the knowledge about aHEV in commercial layer chickens in Nigeria is scarce. In this study, 460 serum samples obtained from 36 apparently healthy commercial layer chicken flocks in three states (Ogun, Osun and Oyo States) of southwestern Nigeria were analysed by enzyme linked immunosorbent assay for the presence of anti-aHEV immunoglobulin Y (IgY) antibodies. In total, the overall seroprevalence of anti-aHEV antibodies was 14.6%. The serological analysis revealed that 75% of the flocks examined were positive for anti-aHEV IgY antibodies from chickens of various ages in all three states. The percentage of the seropositive chickens in the three states varied from flock to flock ranging from 60% to 88.8% and seropositive chickens were detected at any age (24–52 weeks of age) without significant differences between the age groups. This is the first report assessing the presence of aHEV antibodies in chickens from Nigeria. The detection of anti-aHEV antibodies in commercial layer chickens in this study emphasizes the importance of serosurveillance in disease monitoring due to the economic threat posed by aHEV as a result of decreased egg production and increased mortality in affected commercial layer chicken farms. However, further studies are essential to reveal the clinical implications and to assess the real burden of aHEV in Nigeria. Public Library of Science 2021-02-26 /pmc/articles/PMC7909675/ /pubmed/33635917 http://dx.doi.org/10.1371/journal.pone.0247889 Text en © 2021 Osamudiamen et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Osamudiamen, Fisayo Temilade
Akanbi, Olusola Aanuoluwapo
Oluwayelu, Daniel Oladimeji
Bock, C. -Thomas
Klink, Patrycja
Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria
title Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria
title_full Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria
title_fullStr Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria
title_full_unstemmed Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria
title_short Serological evidence of avian HEV antibodies in apparently healthy chickens in southwest Nigeria
title_sort serological evidence of avian hev antibodies in apparently healthy chickens in southwest nigeria
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909675/
https://www.ncbi.nlm.nih.gov/pubmed/33635917
http://dx.doi.org/10.1371/journal.pone.0247889
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