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A SINE Insertion in F8 Gene Leads to Severe Form of Hemophilia A in a Family of Rhodesian Ridgebacks

Hemophilia A is the most common coagulation factor disorder in humans and dogs. The disease is characterized by the lack or diminished activity of Factor VIII (FVIII), caused by variants in the F8 gene and inherited as an X chromosomal trait. Two related male Rhodesian Ridgebacks were diagnosed with...

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Detalles Bibliográficos
Autores principales:	Kehl, Alexandra, Haaland, Anita Haug, Langbein-Detsch, Ines, Mueller, Elisabeth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909816/ https://www.ncbi.nlm.nih.gov/pubmed/33494213 http://dx.doi.org/10.3390/genes12020134

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