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The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells
Bioactive metabolites have wide-ranging biological activities and are a potential source of future research and therapeutic tools. Here, we use nanovibrational stimulation to induce osteogenic differentiation of mesenchymal stem cells, in the absence of off-target, nonosteogenic differentiation. We...
Autores principales: | Hodgkinson, Tom, Tsimbouri, P. Monica, Llopis-Hernandez, Virginia, Campsie, Paul, Scurr, David, Childs, Peter G., Phillips, David, Donnelly, Sam, Wells, Julia A., O’Brien, Fergal J., Salmeron-Sanchez, Manuel, Burgess, Karl, Alexander, Morgan, Vassalli, Massimo, Oreffo, Richard O. C., Reid, Stuart, France, David J., Dalby, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909882/ https://www.ncbi.nlm.nih.gov/pubmed/33637520 http://dx.doi.org/10.1126/sciadv.abb7921 |
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