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Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions

OBJECTIVE: The study objective was to estimate the burden of human rabies in Ethiopia from 2015–2019. Study Design. A descriptive study design was applied to measure the size of the problem. METHOD: Retrospective data were used from the Ethiopian Public Health Institute rabies case record book that...

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Autores principales: Aklilu, Mesfin, Tadele, Wogayehu, Alemu, Amelework, Abdela, Sintayehu, Getahun, Garuma, Hailemariam, Alemnesh, Tadesse, Yirgalem, Kitila, Gutu, Birhanu, Endalkachew, Fli, Ibsa, Getachew, Abebe, Mulugeta, Yimer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910060/
https://www.ncbi.nlm.nih.gov/pubmed/33679992
http://dx.doi.org/10.1155/2021/6662073
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author Aklilu, Mesfin
Tadele, Wogayehu
Alemu, Amelework
Abdela, Sintayehu
Getahun, Garuma
Hailemariam, Alemnesh
Tadesse, Yirgalem
Kitila, Gutu
Birhanu, Endalkachew
Fli, Ibsa
Getachew, Abebe
Mulugeta, Yimer
author_facet Aklilu, Mesfin
Tadele, Wogayehu
Alemu, Amelework
Abdela, Sintayehu
Getahun, Garuma
Hailemariam, Alemnesh
Tadesse, Yirgalem
Kitila, Gutu
Birhanu, Endalkachew
Fli, Ibsa
Getachew, Abebe
Mulugeta, Yimer
author_sort Aklilu, Mesfin
collection PubMed
description OBJECTIVE: The study objective was to estimate the burden of human rabies in Ethiopia from 2015–2019. Study Design. A descriptive study design was applied to measure the size of the problem. METHOD: Retrospective data were used from the Ethiopian Public Health Institute rabies case record book that was registered between 2015 to 2019. RESULT: Eighty-seven (87) cases of human rabies were diagnosed clinically in the Ethiopian Public Health Institute over the period of five years (2015–2019) with 100% case fatality. Of these, 83 (95.4%) cases were attributed to dog bites, whereas 1 (1.1%) to a cat and 3 (3.4%) to wild animals. The fatalities were from Oromia (n = 51 (58.6%), 13 (14.9%) were from Amhara, 15 (17.2%) were from Addis Ababa, and 8 (9.2%) from the Southern region. All referred cases had no record of immunization against rabies except eight. Ineffective postexposure treatment was the reason for 5 (5.7%) deaths. Out of 1,652 brain samples of different animals, mainly dogs, submitted for examination, 1,122 (68%) were found to be positive for rabies by the FAT. Dog bites were more common among males than females. The number of dog bite victims who had visited the EPHI counseling office and recommended to take postexposure prophylaxis against rabies both from Addis Ababa and the surrounding areas were 9,592 and 4,192, respectively. Out of these, 5,708 were males and 3,884 females for the capital Addis Ababa. Similarly, 2,439 males and 1,753 females account for areas surrounding Addis Ababa. Among those exposed from Addis Ababa, 1,079 (11.2%) were in the age group less than five, 1696 (17.7%) were in the age group 6–13, and 6,817 (71.1%) in the age group 14 and greater. Victims from outside of the capital Addis Ababa account for 644 (15.4%) for the age group less than 5 years, 964 (23%) for the age group 6–13 and, 2,584 (61.6%) for the age group 14 and greater. CONCLUSION: Mechanisms must be sought to reduce the cost of PEP and means of obtaining funds so as to initiate timely treatment for rabies exposed individuals of low socioeconomic status. Besides prevention, strategies should focus on public education and strict dog population control.
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spelling pubmed-79100602021-03-04 Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions Aklilu, Mesfin Tadele, Wogayehu Alemu, Amelework Abdela, Sintayehu Getahun, Garuma Hailemariam, Alemnesh Tadesse, Yirgalem Kitila, Gutu Birhanu, Endalkachew Fli, Ibsa Getachew, Abebe Mulugeta, Yimer J Trop Med Research Article OBJECTIVE: The study objective was to estimate the burden of human rabies in Ethiopia from 2015–2019. Study Design. A descriptive study design was applied to measure the size of the problem. METHOD: Retrospective data were used from the Ethiopian Public Health Institute rabies case record book that was registered between 2015 to 2019. RESULT: Eighty-seven (87) cases of human rabies were diagnosed clinically in the Ethiopian Public Health Institute over the period of five years (2015–2019) with 100% case fatality. Of these, 83 (95.4%) cases were attributed to dog bites, whereas 1 (1.1%) to a cat and 3 (3.4%) to wild animals. The fatalities were from Oromia (n = 51 (58.6%), 13 (14.9%) were from Amhara, 15 (17.2%) were from Addis Ababa, and 8 (9.2%) from the Southern region. All referred cases had no record of immunization against rabies except eight. Ineffective postexposure treatment was the reason for 5 (5.7%) deaths. Out of 1,652 brain samples of different animals, mainly dogs, submitted for examination, 1,122 (68%) were found to be positive for rabies by the FAT. Dog bites were more common among males than females. The number of dog bite victims who had visited the EPHI counseling office and recommended to take postexposure prophylaxis against rabies both from Addis Ababa and the surrounding areas were 9,592 and 4,192, respectively. Out of these, 5,708 were males and 3,884 females for the capital Addis Ababa. Similarly, 2,439 males and 1,753 females account for areas surrounding Addis Ababa. Among those exposed from Addis Ababa, 1,079 (11.2%) were in the age group less than five, 1696 (17.7%) were in the age group 6–13, and 6,817 (71.1%) in the age group 14 and greater. Victims from outside of the capital Addis Ababa account for 644 (15.4%) for the age group less than 5 years, 964 (23%) for the age group 6–13 and, 2,584 (61.6%) for the age group 14 and greater. CONCLUSION: Mechanisms must be sought to reduce the cost of PEP and means of obtaining funds so as to initiate timely treatment for rabies exposed individuals of low socioeconomic status. Besides prevention, strategies should focus on public education and strict dog population control. Hindawi 2021-02-19 /pmc/articles/PMC7910060/ /pubmed/33679992 http://dx.doi.org/10.1155/2021/6662073 Text en Copyright © 2021 Mesfin Aklilu et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Aklilu, Mesfin
Tadele, Wogayehu
Alemu, Amelework
Abdela, Sintayehu
Getahun, Garuma
Hailemariam, Alemnesh
Tadesse, Yirgalem
Kitila, Gutu
Birhanu, Endalkachew
Fli, Ibsa
Getachew, Abebe
Mulugeta, Yimer
Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
title Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
title_full Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
title_fullStr Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
title_full_unstemmed Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
title_short Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
title_sort situation of rabies in ethiopia: a five-year retrospective study of human rabies in addis ababa and the surrounding regions
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910060/
https://www.ncbi.nlm.nih.gov/pubmed/33679992
http://dx.doi.org/10.1155/2021/6662073
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