Cargando…

Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review

Malignant musculoskeletal tumour may cause considerable burden to general health. The fast growth combined with the tumour characteristics and its invasion capability resulted in the poor prognosis of malignant musculoskeletal tumour. Malignant musculoskeletal tumour may cause significant disability...

Descripción completa

Detalles Bibliográficos
Autores principales: Kamal, Achmad Fauzi, Ramang, Didi Saputra, Prasetyo, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910073/
https://www.ncbi.nlm.nih.gov/pubmed/33688439
http://dx.doi.org/10.1155/2021/6678167
_version_ 1783656053347450880
author Kamal, Achmad Fauzi
Ramang, Didi Saputra
Prasetyo, Marcel
author_facet Kamal, Achmad Fauzi
Ramang, Didi Saputra
Prasetyo, Marcel
author_sort Kamal, Achmad Fauzi
collection PubMed
description Malignant musculoskeletal tumour may cause considerable burden to general health. The fast growth combined with the tumour characteristics and its invasion capability resulted in the poor prognosis of malignant musculoskeletal tumour. Malignant musculoskeletal tumour may cause significant disability by destroying normal tissue that plays important role in body kinematics. Thromboembolism, including deep vein thrombosis, pulmonary embolism, and other kinds of venous thromboembolism, is one of the most underestimated complications of musculoskeletal tumour. Normally, thrombosis ensues when pathologic factors overcame the body hemostatic regulatory capabilities, which will predispose the body to the formation of thrombus. Venous thromboembolism in musculoskeletal tumour may develop as a result of interaction between the tumour pathologic capabilities and its interaction with normal bodily functions. In this study, we reviewed the burden of musculoskeletal tumour and its complication on global health. Then, the review will focus on the pathologic and clinical aspect of thromboembolism in malignant musculoskeletal tumour, including pathophysiology, diagnosis, and treatment based on recent findings and literature.
format Online
Article
Text
id pubmed-7910073
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-79100732021-03-08 Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review Kamal, Achmad Fauzi Ramang, Didi Saputra Prasetyo, Marcel Adv Orthop Review Article Malignant musculoskeletal tumour may cause considerable burden to general health. The fast growth combined with the tumour characteristics and its invasion capability resulted in the poor prognosis of malignant musculoskeletal tumour. Malignant musculoskeletal tumour may cause significant disability by destroying normal tissue that plays important role in body kinematics. Thromboembolism, including deep vein thrombosis, pulmonary embolism, and other kinds of venous thromboembolism, is one of the most underestimated complications of musculoskeletal tumour. Normally, thrombosis ensues when pathologic factors overcame the body hemostatic regulatory capabilities, which will predispose the body to the formation of thrombus. Venous thromboembolism in musculoskeletal tumour may develop as a result of interaction between the tumour pathologic capabilities and its interaction with normal bodily functions. In this study, we reviewed the burden of musculoskeletal tumour and its complication on global health. Then, the review will focus on the pathologic and clinical aspect of thromboembolism in malignant musculoskeletal tumour, including pathophysiology, diagnosis, and treatment based on recent findings and literature. Hindawi 2021-02-19 /pmc/articles/PMC7910073/ /pubmed/33688439 http://dx.doi.org/10.1155/2021/6678167 Text en Copyright © 2021 Achmad Fauzi Kamal et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kamal, Achmad Fauzi
Ramang, Didi Saputra
Prasetyo, Marcel
Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review
title Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review
title_full Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review
title_fullStr Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review
title_full_unstemmed Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review
title_short Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review
title_sort thromboembolism in malignant musculoskeletal tumour: a literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910073/
https://www.ncbi.nlm.nih.gov/pubmed/33688439
http://dx.doi.org/10.1155/2021/6678167
work_keys_str_mv AT kamalachmadfauzi thromboembolisminmalignantmusculoskeletaltumouraliteraturereview
AT ramangdidisaputra thromboembolisminmalignantmusculoskeletaltumouraliteraturereview
AT prasetyomarcel thromboembolisminmalignantmusculoskeletaltumouraliteraturereview