The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches

The recruitment of neutrophil to the primary cancer has been shown to be steered by neoplastic cells or tumor-educated mesenchymal stromal cells and has a prometastatic effect. However, the neutrophil chemotaxis and their interaction with tumor cells in the distal metastasized tissues remain elusive...

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Detalles Bibliográficos
Autores principales: Xing, Xin, Bai, Yongrui, Song, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910074/
https://www.ncbi.nlm.nih.gov/pubmed/33688508
http://dx.doi.org/10.1155/2021/6687474
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author Xing, Xin
Bai, Yongrui
Song, Jian
author_facet Xing, Xin
Bai, Yongrui
Song, Jian
author_sort Xing, Xin
collection PubMed
description The recruitment of neutrophil to the primary cancer has been shown to be steered by neoplastic cells or tumor-educated mesenchymal stromal cells and has a prometastatic effect. However, the neutrophil chemotaxis and their interaction with tumor cells in the distal metastasized tissues remain elusive. In this review, we discussed emerging research on the interaction between neutrophil recruitment and tumor metastasis, which is essential for studying tumor cell invasion and related immunotherapy.
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spelling pubmed-79100742021-03-08 The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches Xing, Xin Bai, Yongrui Song, Jian J Immunol Res Review Article The recruitment of neutrophil to the primary cancer has been shown to be steered by neoplastic cells or tumor-educated mesenchymal stromal cells and has a prometastatic effect. However, the neutrophil chemotaxis and their interaction with tumor cells in the distal metastasized tissues remain elusive. In this review, we discussed emerging research on the interaction between neutrophil recruitment and tumor metastasis, which is essential for studying tumor cell invasion and related immunotherapy. Hindawi 2021-02-19 /pmc/articles/PMC7910074/ /pubmed/33688508 http://dx.doi.org/10.1155/2021/6687474 Text en Copyright © 2021 Xin Xing et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Xing, Xin
Bai, Yongrui
Song, Jian
The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
title The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
title_full The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
title_fullStr The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
title_full_unstemmed The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
title_short The Heterogeneity of Neutrophil Recruitment in the Tumor Microenvironment and the Formation of Premetastatic Niches
title_sort heterogeneity of neutrophil recruitment in the tumor microenvironment and the formation of premetastatic niches
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910074/
https://www.ncbi.nlm.nih.gov/pubmed/33688508
http://dx.doi.org/10.1155/2021/6687474
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