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Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid

PURPOSE: Conventional genetic analyzers require surgically obtained tumor tissues to confirm the molecular diagnosis of diffuse glioma. Recent technical breakthroughs have enabled increased utilization of cell-free tumor DNA (ctDNA) in body fluids as a reliable resource for molecular diagnosis in va...

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Detalles Bibliográficos
Autores principales: Fujioka, Yutaka, Hata, Nobuhiro, Akagi, Yojiro, Kuga, Daisuke, Hatae, Ryusuke, Sangatsuda, Yuhei, Michiwaki, Yuhei, Amemiya, Takeo, Takigawa, Kosuke, Funakoshi, Yusuke, Sako, Aki, Iwaki, Toru, Iihara, Koji, Mizoguchi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910241/
https://www.ncbi.nlm.nih.gov/pubmed/33417137
http://dx.doi.org/10.1007/s11060-020-03682-7

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