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Probing hepatic metabolism of [2-(13)C]dihydroxyacetone in vivo with (1)H-decoupled hyperpolarized (13)C-MR

OBJECTIVES: To enhance detection of the products of hyperpolarized [2-(13)C]dihydroxyacetone metabolism for assessment of three metabolic pathways in the liver in vivo. Hyperpolarized [2-(13)C]DHAc emerged as a promising substrate to follow gluconeogenesis, glycolysis and the glycerol pathways. Howe...

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Detalles Bibliográficos
Autores principales: Marco-Rius, Irene, Wright, Alan J., Hu, De-en, Savic, Dragana, Miller, Jack J., Timm, Kerstin N., Tyler, Damian, Brindle, Kevin M., Comment, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910257/
https://www.ncbi.nlm.nih.gov/pubmed/32910316
http://dx.doi.org/10.1007/s10334-020-00884-y