Kinetic Modelling and Test–Retest Reproducibility for the Dopamine D(1)R Radioligand [(11)C]SCH23390 in Healthy and Diseased Mice

PURPOSE: Our aim in this study was to compare different non-invasive pharmacokinetic models and assess test–retest reproducibility of the radioligand [(11)C]SCH23390 for the quantification of dopamine D(1)-like receptor (D(1)R) in both wild-type (WT) mice and heterozygous (HET) Q175DN mice as Huntin...

Descripción completa

Detalles Bibliográficos
Autores principales: Bertoglio, Daniele, Verhaeghe, Jeroen, Miranda, Alan, Wyffels, Leonie, Stroobants, Sigrid, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Skinbjerg, Mette, Liu, Longbin, Staelens, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910372/
https://www.ncbi.nlm.nih.gov/pubmed/33179158
http://dx.doi.org/10.1007/s11307-020-01561-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910372/
https://www.ncbi.nlm.nih.gov/pubmed/33179158
http://dx.doi.org/10.1007/s11307-020-01561-1

Ejemplares similares