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Kinetic Modelling and Test–Retest Reproducibility for the Dopamine D(1)R Radioligand [(11)C]SCH23390 in Healthy and Diseased Mice
PURPOSE: Our aim in this study was to compare different non-invasive pharmacokinetic models and assess test–retest reproducibility of the radioligand [(11)C]SCH23390 for the quantification of dopamine D(1)-like receptor (D(1)R) in both wild-type (WT) mice and heterozygous (HET) Q175DN mice as Huntin...
Autores principales: | Bertoglio, Daniele, Verhaeghe, Jeroen, Miranda, Alan, Wyffels, Leonie, Stroobants, Sigrid, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Skinbjerg, Mette, Liu, Longbin, Staelens, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910372/ https://www.ncbi.nlm.nih.gov/pubmed/33179158 http://dx.doi.org/10.1007/s11307-020-01561-1 |
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