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Reconstitution and optimisation of the biosynthesis of bacterial sugar pseudaminic acid (Pse5Ac7Ac) enables preparative enzymatic synthesis of CMP-Pse5Ac7Ac

Pseudaminic acids present on the surface of pathogenic bacteria, including gut pathogens Campylobacter jejuni and Helicobacter pylori, are postulated to play influential roles in the etiology of associated infectious diseases through modulating flagella assembly and recognition of bacteria by the hu...

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Detalles Bibliográficos
Autores principales: Chidwick, Harriet S., Flack, Emily K. P., Keenan, Tessa, Walton, Julia, Thomas, Gavin H., Fascione, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910423/
https://www.ncbi.nlm.nih.gov/pubmed/33637817
http://dx.doi.org/10.1038/s41598-021-83707-x