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Size-based characterization of adalimumab and TNF-α interactions using flow induced dispersion analysis: assessment of avidity-stabilized multiple bound species

The understanding and characterization of protein interactions is crucial for elucidation of complicated biomolecular processes as well as for the development of new biopharmaceutical therapies. Often, protein interactions involve multiple binding, avidity, oligomerization, and are dependent on the...

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Detalles Bibliográficos
Autores principales: Pedersen, Morten E., Haegebaert, Ragna M. S., Østergaard, Jesper, Jensen, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910425/
https://www.ncbi.nlm.nih.gov/pubmed/33637878
http://dx.doi.org/10.1038/s41598-021-84113-z

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