Toll-like receptor-9 stimulated plasmacytoid dendritic cell precursors suppress autoimmune neuroinflammation in a murine model of multiple sclerosis

Early innate education of hematopoietic progenitors within the bone marrow (BM) stably primes them for either trained immunity or instead immunoregulatory functions. We herein demonstrate that in vivo or in vitro activation within the BM via Toll-like receptor-9 generates a population of plasmacytoi...

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Detalles Bibliográficos
Autores principales: Letscher, Hélène, Agbogan, Viviane A., Korniotis, Sarantis, Gastineau, Pauline, Tejerina, Emmanuel, Gras, Christophe, Mégret, Jérôme, Moe, Alison, Drobyski, William R., Zavala, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910458/
https://www.ncbi.nlm.nih.gov/pubmed/33637789
http://dx.doi.org/10.1038/s41598-021-84023-0

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