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Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia

Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson’s disease, and other movement disorders. Here, we demonstrate the potential benefits of DBS in a model of ataxia by targeting the cerebellum, a major motor center in the brain. We use the Car8 mouse model of hereditary ataxia to te...

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Detalles Bibliográficos
Autores principales:	Miterko, Lauren N., Lin, Tao, Zhou, Joy, van der Heijden, Meike E., Beckinghausen, Jaclyn, White, Joshua J., Sillitoe, Roy V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910465/ https://www.ncbi.nlm.nih.gov/pubmed/33637754 http://dx.doi.org/10.1038/s41467-021-21417-8

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