Cargando…

Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts

Recent studies identified cyclase-associated proteins (CAPs) as important regulators of actin dynamics that control assembly and disassembly of actin filaments (F-actin). While these studies significantly advanced our knowledge of their molecular functions, the physiological relevance of CAPs largel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kepser, Lara-Jane, Khudayberdiev, Sharof, Hinojosa, Laura Soto, Macchi, Chiara, Ruscica, Massimiliano, Marcello, Elena, Culmsee, Carsten, Grosse, Robert, Rust, Marco B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910472/ https://www.ncbi.nlm.nih.gov/pubmed/33637797 http://dx.doi.org/10.1038/s41598-021-84213-w

Ejemplares similares

Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons
por: Schneider, Felix, et al.
Publicado: (2021)

CAPt’n of Actin Dynamics: Recent Advances in the Molecular, Developmental and Physiological Functions of Cyclase-Associated Protein (CAP)
por: Rust, Marco B., et al.
Publicado: (2020)

MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells
por: Liu, Chen-Ying, et al.
Publicado: (2016)

Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway
por: Morimatsu, Maho, et al.
Publicado: (2020)

Regulation of Dendritic Synaptic Morphology and Transcription by the SRF Cofactor MKL/MRTF
por: Tabuchi, Akiko, et al.
Publicado: (2021)

Actomyosin and the MRTF-SRF pathway downregulate FGFR1 in mesenchymal stromal cells
por: Zonderland, Jip, et al.
Publicado: (2020)

MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion
por: Hinojosa, Laura Soto, et al.
Publicado: (2017)

Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology
por: Heinze, Anika, et al.
Publicado: (2022)

Prevention of bleomycin‐induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway
por: Pawelec, Kendell M., et al.
Publicado: (2022)

Circadian clock control of MRTF/SRF pathway suppresses beige adipocyte thermogenic recruitment
por: Xiong, Xuekai, et al.
Publicado: (2022)

HDAC6 Regulates the MRTF-A/SRF Axis and Vascular Smooth Muscle Cell Plasticity
por: Zhang, Mengxue, et al.
Publicado: (2018)

Exercise‐dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF‐SRF signalling
por: Solagna, Francesca, et al.
Publicado: (2020)

An association study of cyclase‐associated protein 2 and frailty
por: Pelucchi, Silvia, et al.
Publicado: (2023)

Cyclosporine A inhibits MRTF‐SRF signaling through Na(+)/K(+) ATPase inhibition and actin remodeling
por: Burat, Bastien, et al.
Publicado: (2019)

Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation
por: Kuchler, Oliver, et al.
Publicado: (2022)

Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations
por: Le Dour, Caroline, et al.
Publicado: (2022)

Mutual dependence of the MRTF–SRF and YAP–TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics
por: Foster, Charles T., et al.
Publicado: (2017)

The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression
por: Fernández-Barrera, Jaime, et al.
Publicado: (2018)

In vitro and in vivo delivery of a sustained release nanocarrier-based formulation of an MRTF/SRF inhibitor in conjunctival fibrosis
por: Tagalakis, Aristides D., et al.
Publicado: (2018)

Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis
por: Yu-Wai-Man, Cynthia, et al.
Publicado: (2017)

Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion
por: Marco, Sergi, et al.
Publicado: (2021)

A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation
por: Guenther, Carla, et al.
Publicado: (2019)

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function
por: Kepser, Lara-Jane, et al.
Publicado: (2019)

Paracrine HB-EGF signaling reduce enhanced contractile and energetic state of activated decidual fibroblasts by rebalancing SRF-MRTF-TCF transcriptional axis
por: Afzal, Junaid, et al.
Publicado: (2022)

A comprehensive characterization of the nuclear microRNA repertoire of post-mitotic neurons
por: Khudayberdiev, Sharof A., et al.
Publicado: (2013)

The dynamic recruitment of TRBP to neuronal membranes mediates dendritogenesis during development
por: Antoniou, Anna, et al.
Publicado: (2017)

Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling
por: Gao, Xuemin, et al.
Publicado: (2020)

Optical properties of SrF(2) and SrF(2):Ce(3+) crystals codoped with In(3+)
por: Myasnikova, Alexandra, et al.
Publicado: (2020)

Mef2-mediated transcription of the miR379–410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels
por: Fiore, Roberto, et al.
Publicado: (2009)

Performance of the LEP2 SRF system
por: Boussard, Daniel
Publicado: (1997)

MRTF-A can activate Nrf2 to increase the resistance to doxorubicin
por: Xu, Yao, et al.
Publicado: (2016)

Gene regulation and deregulation by MAL/MRTF coactivators
por: Posern, G
Publicado: (2009)

MRTF: Basic Biology and Role in Kidney Disease
por: Miranda, Maria Zena, et al.
Publicado: (2021)

Prognostic impact of adenylyl cyclase-associated protein 2 (CAP2) in glioma: A clinicopathological study
por: Saker, Zahraa, et al.
Publicado: (2020)

Lamina-associated polypeptide 2α is required for intranuclear MRTF-A activity
por: Sidorenko, Ekaterina, et al.
Publicado: (2022)

SRF for Muon Colliders
por: Padamsee, H
Publicado: (2000)

NLK is required for Ras/ERK/SRF/ELK signaling to tune skeletal muscle development by phosphorylating SRF and antagonizing the SRF/MKL pathway
por: Li, Shang-Ze, et al.
Publicado: (2022)

Proteomics and Lipidomics to unveil the contribution of PCSK9 beyond cholesterol lowering: a narrative review
por: Gianazza, Erica, et al.
Publicado: (2023)

Profibrotic epithelial phenotype: a central role for MRTF and TAZ
por: Bialik, Janne Folke, et al.
Publicado: (2019)

MRTF specifies a muscle-like contractile module in Porifera
por: Colgren, J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_manana80b6d96k1krd9i60crko