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Stability data of extemporaneous oral suspension of pentobarbital in Syrspend SF Alka for imaging sedation procedure

Pentobarbital is used as an alternative in pediatric sedative imaging procedures. Pentobarbital is only available as pharmaceutical powder. Regardless of its clinical use, its manipulation is necessary byhospital pharmacists that must prepare adapted dosage forms for pediatrics. The data presented i...

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Detalles Bibliográficos
Autores principales: Querin, Benjamin, Schweitzer-Chaput, Arnaud, Nedjar, Chahrazed, Schlatter, Joël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910507/
https://www.ncbi.nlm.nih.gov/pubmed/33681434
http://dx.doi.org/10.1016/j.dib.2021.106884
Descripción
Sumario:Pentobarbital is used as an alternative in pediatric sedative imaging procedures. Pentobarbital is only available as pharmaceutical powder. Regardless of its clinical use, its manipulation is necessary byhospital pharmacists that must prepare adapted dosage forms for pediatrics. The data presented in this article suggest that extemporaneous suspensions of sodium pentobarbital in oral liquid base are stable for at least 120 days.