Optical tweezers-controlled hotspot for sensitive and reproducible surface-enhanced Raman spectroscopy characterization of native protein structures

Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful tool to detect biomolecules in aqueous environments. However, it is challenging to identify protein structures at low concentrations, especially for the proteins existing in an equilibrium mixture of various conformations. Here, we...

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Detalles Bibliográficos
Autores principales: Dai, Xin, Fu, Wenhao, Chi, Huanyu, Mesias, Vince St. Dollente, Zhu, Hongni, Leung, Cheuk Wai, Liu, Wei, Huang, Jinqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910584/
https://www.ncbi.nlm.nih.gov/pubmed/33637710
http://dx.doi.org/10.1038/s41467-021-21543-3

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