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Structure-guided insights into heterocyclic ring-cleavage catalysis of the non-heme Fe (II) dioxygenase NicX
Biodegradation of aromatic and heterocyclic compounds requires an oxidative ring cleavage enzymatic step. Extensive biochemical research has yielded mechanistic insights about catabolism of aromatic substrates; yet much less is known about the reaction mechanisms underlying the cleavage of heterocyc...
Autores principales: | Liu, Gongquan, Zhao, Yi-Lei, He, Fangyuan, Zhang, Peng, Ouyang, Xingyu, Tang, Hongzhi, Xu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910607/ https://www.ncbi.nlm.nih.gov/pubmed/33637718 http://dx.doi.org/10.1038/s41467-021-21567-9 |
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