Characterization of Gene Therapy Associated Uveitis Following Intravitreal Adeno-Associated Virus Injection in Mice

PURPOSE: To characterize the intraocular immune cell infiltrate induced by intravitreal adeno-associated virus (AAV) gene therapy. METHODS: AAV vectors carrying plasmids expressing green fluorescent protein under the control of PR2.1 were injected intravitreally into AAV naive and AAV primed C57Bl/6...

Descripción completa

Detalles Bibliográficos
Autores principales: Tummala, Gayathri, Crain, Adam, Rowlan, Jessica, Pepple, Kathryn L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910624/
https://www.ncbi.nlm.nih.gov/pubmed/33630023
http://dx.doi.org/10.1167/iovs.62.2.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7910624/
https://www.ncbi.nlm.nih.gov/pubmed/33630023
http://dx.doi.org/10.1167/iovs.62.2.41

Ejemplares similares